At the western end of the India-Asian collision zone, the Tian Shan, Pamir, and Hindu Kush frame the Tajik depression, hosting the Tajik basin (Figure 1a). Deformation rates derived from pointwise Global Navigation Satellite System (GNSS) data along the northern and western margins of the Pamir reach ∼20 mm/yr (Metzger et al., 2020;Zubovich et al., 2010), being among the highest measured inside a continent. The accommodating crustal structures-thrusts and strike-slip faults-host abundant seismicity (e.g., Kufner et al., 2018;Schurr et al., 2014), including six magnitude M7 and 18 M6.5 earthquakes during the past 115 years. All of these occurred in the center and along the northeastern and northwestern rims of the Pamir. Geologic, geophysical, and geodetic observations indicate that the Pamir has moved northward, building an orocline with 65-75-km-thick crust beneath the Pamir Plateau (Mechie et al., 2012;Schneider et al., 2019). At the same time, the Pamir-Plateau crust has collapsed and has laterally (westward) extruded, thickening the crust west of the collision zone (Rutte et al., 2017;Stübner et al., 2013). Over the last ∼12 Ma, westward extrusion into the Tajik depression has inverted the Tajik basin, forming the Tajik fold-thrust belt