Takayasu arteritis in pregnancy

Dey, Madhusudan; Kapur, Anupam; Goyal, Sunil; Wadhwa, RD; Srivastava, Akansha; Agarwal, Raju

doi:10.1016/j.mjafi.2014.04.013

Cited by 8 publications

(18 citation statements)

References 5 publications

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“…Hypertension can also lead to catastrophic complications such as aortic dissections in women with dilated aortic roots. Thus hypertension, together with the autoimmune pathology of TA can directly or indirectly aggravate medical and/or obstetric complications (2,6,9,20,25,30).…”

Section: Discussionmentioning

confidence: 99%

Obstetric and perinatal outcomes in pregnant women with Takayasu’s arteritis: single centre experience over five years

David

Beck

Kumar

et al. 2020

J Turkish German Gynecol Assoc

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To study obstetric and perinatal outcomes among pregnant women with Takayasu arteritis (TA), attending our hospital for pregnancy and childbirth between January 2011 to December 2016. Material and Methods: Retrospective study was carried out by abstracting clinical charts on all pregnant women with TA who underwent antenatal care and/or delivery in our hospital during this period. American College of Rheumatology criteria was used for diagnosis of TA. Sixteen women with TA were included in the study. Maternal demographic data, stage of disease, complications related to disease, details of treatment taken prior to pregnancy, pregnancy outcomes, and neonatal outcomes were studied. Results: Forty-four percentage (7/16) belonged to type 5 angiographic type, however the same proportion (7/16) had undergone surgical corrections prior to pregnancy and the majority (15/16) were on medical management. Only three women (19%) were diagnosed during pregnancy. Most did not have active disease measured by Kerr's criteria (n=12; 75%), and Indıan Takayasu clinical activity scores A. Chronic hypertension was the commonest antenatal complication (56.2%), nearly one-third had growth restricted babies and 25% had preterm labour. There were no cardiovascular events, no maternal deaths, nor fetal or neonatal deaths. Two-thirds of our women were delivered by caesarean section. Conclusion: Preconceptional counselling is of paramount importance in women with TA. Good maternal and fetal outcomes are observed with close antenatal surveillance and multidisciplinary care. Pregnancy should be planned during disease remission, with good antenatal care, close monitoring of clinical symptoms, early diagnosis and treatment of complications.

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Section: Discussionmentioning

confidence: 99%

Obstetric and perinatal outcomes in pregnant women with Takayasu’s arteritis: single centre experience over five years

David

Beck

Kumar

et al. 2020

J Turkish German Gynecol Assoc

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“…It was first described in a Japanese woman in 1908 by the ophthalmologist Mikito Takayasu who reported a case of a 21-year-old woman with the association of retinal arteriovenous anastomosis, syncope, and pulseless superior extremities [ 2 ]. It affects women predominantly (ratio of 4:1, female to male) [ 3 ]. The pathophysiology of TA has been described as a chronic inflammatory disease affecting the aorta and its branches in a progressive pattern, which can lead to secondary hypertension, retinopathy, cardiac pathology, stroke, and death at an early age [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Takayasu arteritis a cause of hypertensive disorder of pregnancy: a case report

et al. 2018

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BackgroundTakayasu arteritis is a rare, chronic, granulomatous systemic vasculitis of unknown etiology and a few cases have been reported in pregnancy. In pregnancies concomitant with Takayasu arteritis or after diagnosis, Takayasu arteritis negatively affects pregnancy by increasing 13-fold the odds of complications such as hypertensive disorders. The best recommendations in this scenario are still to be made.Case presentationWe present a case of 21-year-old, gravid 1, Mexican woman of Mestizo descent with chronic hypertension diagnosed since she was 15-years old who presented severe hypertension during pregnancy (early second trimester); the diagnosis of hypertensive disorder of pregnancy was ruled out requiring first-line and second-line antihypertensive therapy without serious associated maternal or fetal morbidity.ConclusionsTakayasu arteritis and pregnancy play an important role in maternal and fetal outcomes. Efforts should be made to further investigate the Takayasu arteritis diagnosis in pregnant women with refractory hypertension.

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Section: Introductionmentioning

confidence: 99%

“…Takayasu's arteritis (TA) is a rare chronic progressive inflammatory disease of uncertain aetiology, but suspected to have multiple causes [1-11]. Takayasu first described the disease in 1908 [1-8]. TA usually affects aorta and its main branches commonly: carotid, subclavian and renal arteries [1-10].…”

Section: Introductionmentioning

confidence: 99%

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Successful spinal anaesthesia for caesarean section in an African patient with Takayasu�s arteritis

Kassa¹,

Melese²,

Bedada³

2018

Pan Afr Med J

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Takayasu's arteritis (TA) is a rare chronic inflammatory disease affecting mainly the aorta and its main branches. We report a case of a 24-year-old primigravida, an African patient, with TA planned for caesarean section at 37 weeks of gestation. Clinically, she has involvement of aortic arch and its branches and abdominal aorta. She underwent caesarean section and delivered an alive baby boy under successful spinal anaesthesia with insignificant complications. Although it is rare in the African continent, anesthesiologists should be up-to-date with the knowledge of perioperative anesthetic management of TA in pregnant cases requiring operative delivery.

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Takayasu arteritis in pregnancy

Cited by 8 publications

References 5 publications

Obstetric and perinatal outcomes in pregnant women with Takayasu’s arteritis: single centre experience over five years

Obstetric and perinatal outcomes in pregnant women with Takayasu’s arteritis: single centre experience over five years

Takayasu arteritis a cause of hypertensive disorder of pregnancy: a case report

Successful spinal anaesthesia for caesarean section in an African patient with Takayasu�s arteritis

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