Takayasu Disease with Predominant Pulmonary Involvement

Elsässer, S; Solèr, Markus; Bolliger, Chris T.; Jäger, K; Steiger, U; Perruchoud, André P.

doi:10.1159/000029490

Cited by 31 publications

(19 citation statements)

References 11 publications

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“…It is usually associated with aortic involvement, isolated involvement being rare [5][6][7][8]. The lobar, segmental, and subsegmental branches are more commonly involved than the main right and left pulmonary arteries.…”

Section: Discussionmentioning

confidence: 99%

Endovascular stent implantation for severe pulmonary artery stenosis in aortoarteritis (Takayasu's arteritis)

Tyagi

Mehta

Kashyap

et al. 2004

Cathet Cardio Intervent

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Symptomatic pulmonary artery stenosis is a relatively uncommon manifestation of aortoarteritis. We describe a patient of aortoarteritis with severe proximal right pulmonary artery stenosis who presented with dyspnea on exertion and central cyanosis. The pulmonary artery stenosis was successfully relieved by percutaneous transluminal balloon angioplasty and implantation of a balloon-expandable stent. This resulted in immediate improvement in oxygen saturation, disappearance of cyanosis, relief of dyspnea, and marked improvement in right lung perfusion as demonstrated by pre- and postangioplasty technetium lung ventilation-perfusion scans. The changes in the pulmonary arterial wall morphology were detected precisely by intravascular ultrasound imaging.

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Section: Discussionmentioning

confidence: 99%

Endovascular stent implantation for severe pulmonary artery stenosis in aortoarteritis (Takayasu's arteritis)

Tyagi

Mehta

Kashyap

et al. 2004

Cathet Cardio Intervent

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“…The first two cases illustrate that vasculitis involving the pulmonary arteries can mimic thrombo-embolism with progression to surgery in both cases. Vasculitis of the pulmonary artery has been attributed to either Takayasu's arteritis [2,3], or giant cell arteritis [4], with patients presenting with evidence of pulmonary artery obstruction mimicking thrombo-embolic disease, pulmonary hypertension and severe haemoptysis. WG does not usually involve the large elastic arteries and to our knowledge this is the first reported case of WG affecting the main pulmonary arteries, here presenting clinically as a mimic of pulmonary thrombo-embolic disease.…”

Section: Discussionmentioning

confidence: 99%

Thoracic vasculitis presenting as surgical problems

et al. 2009

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We present four patients with vasculitis manifesting with unusual clinical or pathological features, generating surgical problems. Two cases presented with pulmonary hypertension, with investigations and radiological evidence prompting clinical suspicion of pulmonary thrombo-embolic disease. First case, with an antecedant history of Wegener's granulomatosis (WG), demonstrated following "embolectomy", WG involving the large pulmonary elastic arteries. The second case of inoperable "pulmonary thrombo-embolic disease" was subsequently found at limited post mortem to have giant cell arteritis, which affected widespread small peripheral pulmonary arterial vessels. The other two cases were of aortitis occurring in the background of immune-mediated disease, which had been treated with aggressive immunosuppression regimens. The first of these was a case of Cogan's syndrome complicated by descending aortitis, a rarely reported phenomenon, with co-existent acute endocarditis of the aortic valve leaflets. Most cases of endocarditis in this context occur secondary to and in continuity with ascending aortitis. That this case, and a case of ascending aortitis occurring in the context of relapsing polychondritis occurred in the face of aggressive immunosuppression with an apparent clinical response, underscores the need to not accept a clinical picture at face value. This has implications for clinical management, particularly in the follow-up of surgical prosthetic devices such as grafts which may be used in these cases. All four cases emphasise the continued importance of histology and the post-mortem examination in elucidating previously undetected or unsuspected disease.

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“…[23][24][25][26] The characteristics of these reports were that the pathological changes were detected only in the pulmonary artery but not in systemic arteries such as the aorta and its branches, and that these changes in the pulmonary artery, morphologically demonstrated as severe narrowing or total occlusion of the lumen, were most frequently seen at areas of large caliber of the pulmonary arterial tree, such as the left and right or lobar pulmonary arteries. Surgical treatment, mostly by means of a bypass procedure using prosthetic graft, has already been undertaken in some of these lesions.…”

Section: )mentioning

confidence: 99%

Takayasu Arteritis: Consideration of Pulmonary Involvement

Nakajima

2008

Annals of Vascular Diseases

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Takayasu Disease with Predominant Pulmonary Involvement

Cited by 31 publications

References 11 publications

Endovascular stent implantation for severe pulmonary artery stenosis in aortoarteritis (Takayasu's arteritis)

Endovascular stent implantation for severe pulmonary artery stenosis in aortoarteritis (Takayasu's arteritis)

Thoracic vasculitis presenting as surgical problems

Takayasu Arteritis: Consideration of Pulmonary Involvement

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