Taking the headache out of migraine

Borsook, David; Dodick, David W.

doi:10.1212/cpj.0000000000000171

Cited by 12 publications

(10 citation statements)

References 70 publications

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“…Headache is the symptom of pain in the face, head, or neck that causes disability in most people with medical and neurological disorders [10]. In this review, headache was considered when the studies investigated and reported the prevalence of primary headaches such as migraine (with or without aura), tension-type headache, Ictal headache, and post-ictal headache among patients with epilepsy based on any standardized and validated screening instruments used to assess headaches such as Migraine Screening -Questionnaire (MSQ), the International Classification of Headache Disorders 2nd or 3rd edition (ICHD-2, 3), the Headache-Attributed Lost Time (HALT) and the six-item Headache Impact Test.…”

Section: Definition Of Termsmentioning

confidence: 99%

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The epidemiology of headaches among patients with epilepsy: a systematic review and meta-analysis

2020

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Background: Headache is the symptom of pain in the face, head or neck that causes disability in most people with medical and neurological disorders. It frequently co-occurs with most chronic diseases such as epilepsy and significantly impacts the quality of life. However, epidemiologic data from different studies showed different rates of prevalence. Therefore, we conducted this review to summarize the available epidemiologic evidence on the topic and formulate recommendations for future research and clinical practice. Methods: We followed the preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines. We systematically searched the literature using popular databases such as PubMed, EMBASE, Psych-INFO, and SCOPUS. We further scanned the reference lists of the eligible studies to supplement our electronic search. The Comprehensive Meta-Analysis software version 3.0 (CMA 3.0) was used to conduct a meta-analysis. Subgroup and sensitivity analysis were performed and Cochran's Q-and the I 2-test were used to assess the source of heterogeneity. The funnel plot and Egger's regression tests were used to assess potential publication bias. Results: A total of 17 studies conducted both in developed and developing countries including 5564 study participants were combined in this meta-analysis. The pooled estimated prevalence of headache among patients with epilepsy was 48.4%. The pooled estimated prevalence of Inter-Ictal headache (IIH) (42.2%) and Postictal headache (PIH) (43.1%) were higher when compared to tension-type headache (TTH) (26.2%), migraine with aura (26.0%) and migraine without aura (10.4%). The pooled prevalence of headache was 50.6% and 49.5% for developed and developing countries respectively. The pooled prevalence of headache among patients with epilepsy was considerably higher among females (63.0%) when compared to males (33.3%). Moreover, the pooled estimated prevalence of headache among patients with epilepsy was ranging from 46.0% to 52.2% in a leave-one-out sensitivity analysis. Conclusion: The pooled estimated prevalence of headache among patients with epilepsy was considerably high (48.4%). Screening and appropriate management of headaches among patients with epilepsy are warranted.

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Section: Definition Of Termsmentioning

confidence: 99%

“…Headache is the symptom of pain in the face, head, or neck that causes disability in most people with medical and neurological disorders [10]. There are different types of headaches that can occur in individuals but generally can be classified as primary and secondary headaches [11].…”

Section: Introductionmentioning

confidence: 99%

The epidemiology of headaches among patients with epilepsy: a systematic review and meta-analysis

2020

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“…Our study included data on primary and secondary healthcare on a national level, thus providing a broader overview of migraine management in the country. Most of the migraine patients were adults in their productive years and females, as observed in other studies [21][22][23][24]. Antiepileptics and beta blockers were observed to be the most commonly used prophylactic drugs.…”

Section: Discussionmentioning

confidence: 55%

An Investigation into the Prevalence of Migraine and its Prophylactic Treatment Patterns in the Czech Republic

Doležil

Marková

Klimeš

et al. 2020

Preprint

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Background A national primary and secondary healthcare-level study in the Czech Republic has not yet been conducted to evaluate the prevalence of migraine. Considering the success of newly developed calcitonin gene-related peptide (CGRP) pathway-targeted therapies, we analyzed the current treatment patterns (acute and prophylactic) in migraine patients and the number of migraine patients potentially eligible for treatment with these therapies. Methods This retrospective study utilized the Ministry of the Interior Health Insurance Fund claims database of the Czech Republic wherein every citizen is insured, according to local regulations. Migraine patients with or without aura, and potentially on triptan therapy, from 2012–2016, were included in this study. The prevalence approach (index years 2012–2016) included all patients present in each index year. Prophylactic therapies were followed for three and seven years prior to the index year, including the index year, until 2010. The incidence approach (index years 2012–2016) included all patients first diagnosed in each index year. Prophylactic therapies were followed for the next three years, including the index year, until 2017 following incidence approach. The primary endpoint of this study was to determine the rate of migraine prevalence and diagnosis for each index year during the period 20122–2016. The study also evaluated prophylactic and acute treatment patterns and comorbidities among patients in 2016.Results The rate of migraine prevalence was 1% and the rate of diagnosis was 0.2%–0.4%. The prevalence of migraine in adults and females was similar to global prevalence. By prevalence approach, approximately 39% of the patients were on prophylactics, and 11.2% and 21.6% of the patient population had two prior treatment failures (three- and seven-year recall period, respectively). Overall, antiepileptics (26%) and beta blockers (15.8%) were the most prescribed prophylactics, and sumatriptan was the predominant triptan used (12%) for acute treatment. Conclusion Taking into account the number of inhabitants in the Czech Republic (10.7 million), there could be up to 23,000 adult patients eligible for novel CGRP therapies.

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“…2 Migraine is the sixth-most common disabling condition in the world; it causes a huge economic burden on society and families and seriously decreases the patient quality of life. [2][3][4] Acupuncture is a therapeutic technique in which needles are inserted into specific points (acupoints) on the body. 5,6 As an important component of complementary and alternative medicine, acupuncture has recently gained popularity as a palliative intervention modality.…”

Section: Introductionmentioning

confidence: 99%

<p>Acupuncture versus Various Control Treatments in the Treatment of Migraine: A Review of Randomized Controlled Trials from the Past 10 Years</p>

Dong

Tian

et al. 2020

JPR

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Background: Migraine is defined as a recurrent headache of moderate to severe intensity that seriously affects the quality of life. Recent clinical trials have confirmed that acupuncture is effective in treating migraine. We aimed to review the effectiveness of acupuncture in the treatment of migraine by comparing treatment and various control groups in accordance with the newly published guidelines for systematic reviews. Materials and Methods: The following databases were searched for relevant articles published from January 1, 2010 to December 31, 2019: Embase, PubMed, Medline, Cochrane Library, and four Chinese databases. The present review included randomized controlled trials in which acupuncture was the sole treatment or an adjunctive treatment for migraine. Two researchers independently conducted the study selection, data extraction, and quality assessment processes. Disagreements between reviewers were solved by discussion and data reanalysis. The quality of each included study was evaluated using the Cochrane Collaboration risk-of-bias assessment method and the Standards for Reporting Interventions in Controlled Trials of Acupuncture (STRICTA) checklist. Results: Forty-nine studies were analyzed and ranked based on the latest STRICTA and Cochrane Collaboration risk-of-bias assessment standards. The analysis revealed that acupuncture reduced headache frequency compared with no treatment (mean difference [MD] = −1.80, P < 0.00001, 95% confidence interval [CI] −2.34 to −1.26) and western medicine (MD = −1.75, P = 0.003, 95% CI −2.91 to −0.58). Headache frequency did not significantly differ between patients who received real acupuncture versus those who received sham acupuncture (MD = −0.64, P = 0.24, 95% CI −1.70 to 0.42). Conclusion: The present review evaluated the current research on the use of acupuncture for migraine, compared with various control treatments. The evidence for the effectiveness of acupuncture in controlling migraine is still limited due to the low quality of the published studies.

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Taking the headache out of migraine

Cited by 12 publications

References 70 publications

The epidemiology of headaches among patients with epilepsy: a systematic review and meta-analysis

The epidemiology of headaches among patients with epilepsy: a systematic review and meta-analysis

An Investigation into the Prevalence of Migraine and its Prophylactic Treatment Patterns in the Czech Republic

<p>Acupuncture versus Various Control Treatments in the Treatment of Migraine: A Review of Randomized Controlled Trials from the Past 10 Years</p>

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