2018
DOI: 10.1016/j.ihj.2017.09.005
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Takotsubo syndrome

Abstract: Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography reveals normal epicardial arteries with no obstruction or spasm. NT-ProBNP maybe remarkably elevated. Regional wall motion akinesia (RWMA) of left ventricle extends beyond the territory of one coronary artery. Redu… Show more

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Cited by 39 publications
(61 citation statements)
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“…Acute ventricular insult in left ventricle triggers stretching and release of neuroendocrine peptides such as brain-natriuretic peptide (BNP). Levels of NT-proBNP were more than twofold higher in patients with TTS than patients with STEMI (4702 vs. 2138 pg/ml, respectively) in a recent study [19].…”
Section: Laboratorymentioning
confidence: 84%
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“…Acute ventricular insult in left ventricle triggers stretching and release of neuroendocrine peptides such as brain-natriuretic peptide (BNP). Levels of NT-proBNP were more than twofold higher in patients with TTS than patients with STEMI (4702 vs. 2138 pg/ml, respectively) in a recent study [19].…”
Section: Laboratorymentioning
confidence: 84%
“…Diffuse myocardial edema is typically present in both myocarditis and TTS; however, lack of late gadolinium enhancement in TTS is helpful for differential diagnosis from both acute coronary syndrome an acute myocarditis. Though not standard, common practice for timing of cMRI is within 7 days after the index event and 2-6 months later for assessment of improvement in systolic functions [19].…”
Section: Cardiac Magnetic Resonance Imagingmentioning
confidence: 99%
“…Electrocardiogram might show ST-segment changes, T-wave inversions and prolonged QT intervals (5). Cardiac biomarkers such as troponin and NT-pro-brain natriuretric peptide (NT-pro-BNP) are typically elevated (7).…”
Section: Discussionmentioning
confidence: 99%
“…The ▶ Box features diagnostic criteria for TCM suggested by the Mayo Clinic (1). Investigations include electrocardiography, coronary angiography and cardiac MRI (5).…”
Section: Discussionmentioning
confidence: 99%
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