Talgdrüsenhyperplasie des Unterlides

Abstract

When one encounters a sebaceous tumor involving the eyelid the possibility of Muir-Torre syndrome should be considered. Muir-Torre syndrome is an autosomal dominant genodermatosis characterized by at least a single sebaceous gland tumor (either a hyperplasia, an adenoma, an epithelioma, or a carcinoma) and a minimum of one internal malignancy.

Villous Sebaceous Adenoma Arising from the Caruncular Surface Squamous Epithelium

“…The ability of mature, fully differentiated conjunctival epithelium to spawn benign and malignant sebaceous tumors is consistent with its embryologic role in providing sebaceous glands and vellus hairs for the caruncle. A latent capacity to undergo sebaceous differentiation obviously must persist into adulthood, as exemplified by the current lesion and previous reports of "ectopic" epibulbar and tarsal sebaceous tumors [5][6][7][8][9][10][11][12][13][14]. The multipotentiality of the conjunctival epithelium is also exemplified by an epibulbar dacryoadenoma [24].…”

“…A subset of various sebaceous tumors, however, may arise from the epibulbar and tarsal conjunctival surface epithelium in areas lacking sebaceous glands on a normal anatomic basis [5][6][7][8][9][10][11][12][13][14]. The vast majority of sebaceous lesions are hyperplasias, adenomas, sebaceomas, and carcinomas [1,2,[14][15][16]. These lesions must be distinguished from clear cell squamous carcinoma [17].…”

Maskerade eines Talgdrüsenkarzinoms durch ein rasch rezidivierendes „Chalazion”, eine Kasuistik

“…Selten können auch beide Lider gleichzeitig betroffen sein. Beim Auftreten eines Talgdrüsenkarzinoms muss auûerdem das Vorliegen eines Muir-Torre-Syndroms (mit einem Malignom des Magen-Darm-Traktes) ausgeschlossen werden [4].…”