Tamarind seed polysaccharide: A promising natural excipient for pharmaceuticals

Tamarind Seed Polysaccharide: An Emerging Excipient for Pharmaceutical Use

“…This can be well described by the worm-like chain or by the Kuhn's model. 39 It has excellent ability to swell in water and forms the mucilaginous solution after heating up showing a typical non-Newtonian rheological behavior and pseudoplastic properties. [39][40][41][42][43][44][45][46] Therefore, it has hydrophilic, gel-forming and bioadhesive properties.…”

“…39 It has excellent ability to swell in water and forms the mucilaginous solution after heating up showing a typical non-Newtonian rheological behavior and pseudoplastic properties. [39][40][41][42][43][44][45][46] Therefore, it has hydrophilic, gel-forming and bioadhesive properties. [46][47][48][49][50] Because of these properties, it is also in preparation of hydrogels.…”

“…38 Tamarind seed comprises the seed coat or testa (20-30%) and the kernel or endosperm (70-75%) and it contains 67.1 g/Kg crude fibre with higher percentage of carbohydrate in the form of sugars. 39 Tamarind seed polysaccharide is a cell wall storage material present in tamarind seed and is extracted from tamarind seed powder. 39,40 The isolation method of tamarind seed polysaccharide was first derived in laboratory by Rao et al, 1946.…”

“…39 Tamarind seed polysaccharide is a cell wall storage material present in tamarind seed and is extracted from tamarind seed powder. 39,40 The isolation method of tamarind seed polysaccharide was first derived in laboratory by Rao et al, 1946. 41 The procedure was improved by Rao and Srivastava, 42 in 1973 and further modified by Nandi,43 in 1975 on a laboratory scale.…”

“…68 Tamarind seed polysaccharide was investigated as matrix formers in matrix tablets of various drugs. [37][38][39] In most of the cases, matrix tablets are formulated to make sustained release or controlled release formulations for which these require release modifiers or release retardants. Due to its hydrophilic property, tamarind seed polysaccharide was widely used in various matrix tablets as matrix former and release retardant.…”