Abstract:Nelson's syndrome (NS) is a rare complication following bilateral adrenalectomy. 1 We report a case of NS in a 53-yearold female with headache and generalized hyperpigmentation. She had bilateral adrenalectomy for Cushing's syndrome (CS) secondary to adrenal hyperplasia 22 years ago. Early routine surveillance and extensive patient discussion regarding the lifelong impact of NS is imperative.
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