Tandem synthesis of enantioenriched spirolactones via one-pot Heck–Matsuda reactions directly from nitroarenes

Abstract

We report herein a novel, efficient, and expeditious approach for enantioselective intramolecular carbonylative Heck-Matsuda reaction, employing highly accessible, stable, and cost-effective nitroarenes as masked electrophiles. This tandem process combines the...