2021
DOI: 10.4103/ds.ds_1_21
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Tanshinone IIA, a melanogenic ingredient basis of Salvia miltiorrhiza Bunge

Abstract: Background: The roots of Salvia miltiorrhiza Bunge (Lamiaceae) have been often used to treat vitiligo in clinical for many years. However, the main ingredient basis of efficacy has not been known. Objectives: We investigated whether the two main constituents of S. miltiorrhiza, major hydrophobic compound tanshinone IIA (Tan IIA) and the major hydrophilic compound salvianolic acid B (Sal B), had the same melanogenic activity. … Show more

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