Tardive Oculogyric Crisis due to Aripiprazole treatment in an adolescent patient diagnosed with Bipolar Disorder

Canol, Tugce; Sapmaz, Şermin Yalın; Uzun, Aylin Deniz; Kandemır, Hasan

doi:10.5455/pcp.20200522115147

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2021

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“…Only in one case OCG occurred after more than 1 year of therapy. Furthermore, in this patient it was not sufficient to reduce the aripiprazole dosage, but discontinuation was necessary [ 11 ]. The OGCs were characterized by lifting or deviation of the eyes, lasting from 5 min to 2 h. Three of the subjects described also used other antipsychotics: olanzapine, risperidone, quetiapine [ 6 , 12 , 13 ].…”

Section: Case Presentationsmentioning

confidence: 99%

Aripiprazole-Induced Oculogyric Crisis: A Pediatric Case Series and A Brief Narrative Review

et al. 2021

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Oculogyric crisis (OGC) represent an unusual type of dystonic movement disorder, usually reported as an adverse event of antipsychotic drugs, with acute or tardive onset, likely due to a functional disruption of dopaminergic neurotransmission. It is seldom reported in children with aripiprazole, an atypical antipsychotic commonly used in youths. In this manuscript, we report on a case series of three pediatric patients and provide a brief narrative review of the literature, in order to increase the awareness of clinicians and to foster future research in this area.

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