2022
DOI: 10.1101/2022.02.16.480634
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Target-enrichment sequencing yields valuable genomic data for difficult-to-culture bacteria of public health importance

Abstract: Genomic data contribute invaluable information to the epidemiological investigation of pathogens of public health importance. However, whole genome sequencing (WGS) of bacteria typically relies on culture, which represents a major hurdle for generating such data for a wide range of species for which culture is challenging. In this study, we assessed the use of culture-free target-enrichment sequencing as a method for generating genomic data for two bacterial species: 1) Bacillus anthracis, which causes anthrax… Show more

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