Target Motion Variability and On-Line Positioning Accuracy during External-Beam Radiation Therapy of Prostate Cancer with an Endorectal Balloon Device

Abstract

Margin estimate dorsally may exceed 1 cm and on-line position verification with an ERB cannot be recommended for dose escalation>70 Gy.

Precision of Image-Guided Radiotherapy (IGRT) in Six Degrees of Freedom and Limitations in Clinical Practice

“…Internal motion of the prostate independently from the bony anatomy is well known [4,11,22]. In cases where the rectal filling and, consequently, the position of the prostate were obviously different between planning and treatment, these errors were manually measured and corrected.…”

Transabdominal Ultrasonography, Computed Tomography and Electronic Portal Imaging for 3-Dimensional Conformal Radiotherapy for Prostate Cancer

“…For the future BAT protocol in our department the pre-simulation evaluation of the BAT feasibility has been introduced. For the patients with low ultrasound image quality, other systems of imageguided radiotherapy (IGRT) should be explored [5,7,12].…”

“…However, when such approach is applied, the volume of the irradiated normal structures must be reduced in order to limit normal tissue injury [5,9,12,14,15,18]. The main limitations in margin reduction are the setup errors and organ-motion (prostate motion due to rectum and bladder filling).…”

Internal Immobilization: From Rectal Balloon to Hyaluronic Acid

“…With regard to interfractional motion Wachter et al (2002) were able to demonstrate that maximum displacements of the prostate larger than 5 mm in the anteriorposterior direction was reduced from 80 to 20 % by the use of an erB. However, other studies were not able to confirm that interfraction motion can be reduced by the application of an erB (Van Lin et al 2005;El-Bassiouni et al 2006). Van Lin et al (2005) found no differences in systematic and random prostate motion and concluded that erB application did not reduce interfraction prostate motion.…”