Target organ damage in newly diagnosed hypertensive individuals in Yaoundé, sub Saharan Africa

Nganou–Gnindjio, Chris Nadège; Hamadou, Bâ; Tankeu, Aurel T.; Essomba, J.P.; Boombhi, Jerome; Kuaté, Liliane Mfeukeu; Amougou, Sylvie Ndongo; Ouankou, Christian Ngongang; Njouoguep, Rodrigue; Menanga, Alain; Kingué, Samuel

doi:10.1016/j.acvdsp.2018.10.224

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“…However, the mechanisms linking high BP and severe COVID-19 are still unclear [9,31]. Unfortunately, we have not assessed the prevalence of stroke or other target organ damages in our population, but it is clear that the burden of stroke and chronic kidney disease is high in Cameroon given the high prevalence of hypertension, obesity and diabetes [32,33]. Since SARS-CoV-2 viruses enter the lungs and other cells by binding to ACE2 receptors, it was suggested that drugs such as angiotensinconverting enzyme inhibitors (ACEI) and angiotensin-receptor blockers (ARB) may enhance the expression of these ACE2 receptor at the cell surface, which could facilitate virus entry [34].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Cameroon Cardiovascular Risk Factors Linked to Severe forms of COVID-19

Ngatchou

2021

JOCCT

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Objective: Several cardiovascular risk factors (CVFRs) have been linked with severe forms of the coronavirus disease 2019 . We examined the prevalence of adult Cameroonians with obesity, hypertension, and diabetes. Methods:We extracted data of 19132 participants aged 18 years or above (57% men, mean age: 44•5 years) from a nationwide crosssectional study performed by the Cameroon Heart Institute between 2014 and 2019. Participants were recruited in the 10 regions of Cameroon using a multistage-cluster sampling frame. Socio-demographic and anthropometric variables, blood pressure (BP) and fasting capillary glucose were recorded. The distribution of CVRFs, with 95% confidence intervals, was estimated according to sex and age categories. We also examined the prevalence of combined CVRFs. Findings:The age-standardized prevalence of hypertension, obesity, and diabetes was 39•7%, 29•2 %, and 8•8 %, respectively. Among the participants, 56.0 % had at least one of the three considered risk factor, while 18•4 % had two or three. The prevalence of having at least 1 of the 3 CVRFs was 43•1% at age 18-44 years 69% at age 45-64 years. At age 65 years or more, 73•6% and 18•5%, respectively, had at least one or two risk factor(s). Conclusion:The high prevalence of obesity, hypertension and diabetes in Cameroon underlies large proportions of people at risk of developing severe COVID-19 forms. In addition to the continued need to strengthen clinical and public health interventions to reduce the cardiovascular disease (CVD) burden in the population, it may be useful that national COVID-19 guidelines explicitly address screening, preventive and treatment procedures for people at increased risk of CVD.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Cameroon Cardiovascular Risk Factors Linked to Severe forms of COVID-19

Ngatchou

2021

JOCCT

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Target organ damage in newly diagnosed hypertensive individuals in Yaoundé, sub Saharan Africa

Cited by 1 publication

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Prevalence of Cameroon Cardiovascular Risk Factors Linked to Severe forms of COVID-19

Prevalence of Cameroon Cardiovascular Risk Factors Linked to Severe forms of COVID-19

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