Targeted Therapy for Cutaneous Melanoma: Beyond BRAF...

Davies, Michael A.

doi:10.17294/2330-0698.1006

Journal of Patient-Centered Research and Reviews

2014

DOI: 10.17294/2330-0698.1006

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Targeted Therapy for Cutaneous Melanoma: Beyond BRAF...

Michael A. Davies¹

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Cited by 3 publications

(1 citation statement)

References 80 publications

(105 reference statements)

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“…Anderson Cancer Center, looks at "Targeted Therapy for Cutaneous Melanoma: Beyond BRAF…" He discusses new molecular targets and the potential of melanoma treatment personalization. 10 Vemurafenib is an oral medication, taken twice daily, that inhibits the mutant form of the BRAF protein (V600E) that is present in approximately 50% of cutaneous melanomas. Vemurafenib is only effective in patients who have the mutation and it may make tumors grow faster if it is given to a patient who does not have it.…”

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confidence: 99%

Melanoma: Attacking on Many Fronts

Thompson¹

2014

Journal of Patient-Centered Research and Reviews

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Follow this and additional works at: https://aurora.org/jpcrr Part of the Oncology CommonsJournal of Patient-Centered Research and Reviews ( JPCRR) is a peerreviewed scientific journal whose mission is to communicate clinical and bench research findings, with the goal of improving the quality of human health, the care of the individual patient, and the care of populations. Recommended CitationThompson MA. Melanoma: attacking on many fronts.

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confidence: 99%

Melanoma: Attacking on Many Fronts

Thompson¹

2014

Journal of Patient-Centered Research and Reviews

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Patient-derived tumor xenograft models for melanoma drug discovery

Harris

Joseph

Copland

2016

Expert Opinion on Drug Discovery

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There is a strong necessity to reassess current approaches in which preclinical experiments are designed and executed in order to minimize unwarranted clinical trials. With rigorously performed preclinical studies, PDTX models have the capability to effectively confirm or deny drug effective outcomes. The ability to do this, however, will demand better aids to guide experimental design, the redefining of preclinical efficacy, and the understanding that these models should be viewed as complementary to other drug prediction and efficacy tools.

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Cell cycle control as a promising target in melanoma

Lee

Sandhu

McArthur

2015

Current Opinion in Oncology

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Targeted Therapy for Cutaneous Melanoma: Beyond BRAF...

Cited by 3 publications

References 80 publications

Melanoma: Attacking on Many Fronts

Melanoma: Attacking on Many Fronts

Patient-derived tumor xenograft models for melanoma drug discovery

Cell cycle control as a promising target in melanoma

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