2009
DOI: 10.1016/j.biomaterials.2008.10.039
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Targeting and imaging cancer cells by Folate-decorated, quantum dots (QDs)- loaded nanoparticles of biodegradable polymers

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Cited by 223 publications
(131 citation statements)
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“…The human ovarian carcinoma SKOV3 is a widely used folate receptor positive cell line, however for human breast carcinoma MCF-7 cell line, different literature reports quite contradictory folate receptor expression levels. Jie et al employed MCF-7 as a folate receptor overexpressed cell line [31] while Haimei et al used MCF-7 as a negative control [32]. In this study, we tested the folate receptor expression level of the MCF-7 and SKOV3 cell lines.…”
Section: Folate Receptor Expressionmentioning
confidence: 99%
“…The human ovarian carcinoma SKOV3 is a widely used folate receptor positive cell line, however for human breast carcinoma MCF-7 cell line, different literature reports quite contradictory folate receptor expression levels. Jie et al employed MCF-7 as a folate receptor overexpressed cell line [31] while Haimei et al used MCF-7 as a negative control [32]. In this study, we tested the folate receptor expression level of the MCF-7 and SKOV3 cell lines.…”
Section: Folate Receptor Expressionmentioning
confidence: 99%
“…[24][25][26] The advantages of QDs over the conventional dyes employed for imaging include tailoring of the spectrum of emission by alteration of the size and composition of QDs, the high quantum yield of fluorescence and superior brightness exhibited by QDs, a broader spectrum of excitation, and more rapid imaging. [24][25][26][27][28] Moreover, QDs demonstrate a high degree of photostability and resistance to photobleaching, which is imperative for in vivo application.…”
Section: Qds For Tumor Detection and Imagingmentioning
confidence: 99%
“…[24][25][26] The advantages of QDs over the conventional dyes employed for imaging include tailoring of the spectrum of emission by alteration of the size and composition of QDs, the high quantum yield of fluorescence and superior brightness exhibited by QDs, a broader spectrum of excitation, and more rapid imaging. [24][25][26][27][28] Moreover, QDs demonstrate a high degree of photostability and resistance to photobleaching, which is imperative for in vivo application. [24][25][26][27] However, the use of QDs has been restricted, as a consequence of toxicity from semiconductor QDs (particularly cadmium-based QDs) and inadequate in vivo and physical stability profiles, partly because of their hydrophobic nature.…”
Section: Qds For Tumor Detection and Imagingmentioning
confidence: 99%
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