“…Interestingly, among the microbial metabolites that differed between wildtype and mdx groups, SCFA and key precursors in the biosynthesis pathway of SCFA were found to be significantly reduced in the plasma. Notably, in addition to reversing deficits in locomotor activity, SCFA levels, muscle autophagy, and inflammation, Kalkan et al show that DFZ treatment induced a remarkable increase in the concentration of SCFA, butyrate, known to have beneficial roles including anti‐inflammatory and immunomodulatory properties (Fernandes et al , 2020; Kalkan et al , 2023).…”