Tarsal-related cysts: Different diagnoses with similar presentations

AlRubaian, Ahmad; Alkatan, Hind M.; Al-Faky, Yasser H; Alsuhaibani, Adel H.

doi:10.1016/j.sjopt.2019.01.004

Cited by 7 publications

(20 citation statements)

References 15 publications

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“…Twelve case reports 1,2,4–13 and 6 case series were included. 3,14–18 The largest series outlined 15 cases of TEC. 14 The mean age of all patients was 52.3 years (range 18–85 years), with 50.8% being female.…”

Section: Resultsmentioning

confidence: 99%

Tarsal Epithelial Cysts: Prevalence, Case Series, and Synthesis of Existing Literature

Ahmad

Chen

Chang

et al. 2020

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Purpose: Tarsal epithelial cysts (TECs) are squamous epithelial-lined lesions of the eyelid that are often mistaken for chalazia or epidermal inclusion cysts. They remain poorly described in the literature. This study is designed to characterize the prevalence and clinical features of TEC. Methods: We conducted a single-center retrospective review of adult patients with a diagnosis of eyelid neoplasm, eyelid cyst, hordeolum, stye, or chalazion between January 1, 2011 and July 1, 2017. Among this cohort, we identified patients with a histopathologic diagnosis of TEC. We also conducted a PubMed literature review and synthesis of existing clinical data of patients reported to have TEC, noting common clinical and histopathological features. Results: Of 7,516 patients, we identified 6 patients with a histopathological diagnosis of TEC, amounting to a prevalence of 0.08% amongst patients with eyelid lesions. Average age was 49.7 years (range 18–76 years), with a 1:1 male to female ratio. The most common presenting symptom was a painless eyelid mass, and the majority (66.6%) had a preoperative diagnosis of chalazion. All but 1 patient had surgical excision from the posterior approach and there was 1 recurrence in the follow-up period. On review of the literature, we identified 68 prior cases of TEC from 18 clinical studies, with clinical features mirroring our case series. Conclusions: TEC has stereotypical clinical and histologic features that distinguish it from other tarsal lesions. Our review identified TEC as a relatively rare cause of eyelid lesions.

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Section: Resultsmentioning

confidence: 99%

Tarsal Epithelial Cysts: Prevalence, Case Series, and Synthesis of Existing Literature

Ahmad

Chen

Chang

et al. 2020

Ophthalmic Plastic &Amp; Reconstructive Surgery

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“…The true incidence of IKCs is also unknown. However, it has been suggested that these lesions represent the third leading cause of tarsal-related pathologies, after chalazia and sebaceous gland carcinoma [ 3 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…Clinically, the lesions present as a small, non-inflammatory nodule, firm upon palpation and fixed to the tarsus, but with freely movable overlying skin on the upper eyelids of middle-aged male adults [ 3 , 6 ]. Although rare, multiple IKCs associated with the Gorlin–Goltz syndrome (GGS) have been reported [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…Due to their non-specific clinical appearance, IKCs are often misdiagnosed as other eyelid lesions, particularly epidermal inclusion cysts and chalazia. Therefore, it is essential to diagnose the IKCs accurately and distinguish them from these lesions, because the IKC recurs locally if not completely removed [ 3 , 7 , 8 ]. Surgical excision of the cyst and the associated gland has been proposed to prevent recurrences [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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Intratarsal Keratinous Cyst Clinically Misdiagnosed as a Chalazion

Cunha,

Andrade,

da Cunha Filho

et al. 2024

Dermatopathology

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The intratarsal keratinous cyst (IKC) is a recently described entity, often clinically misdiagnosed as a chalazion. We report a case of a 61-year-old male patient with a chief complaint of a small lesion on the upper eyelid that evolved over six months. On physical examination, an asymptomatic, firm nodule was identified on the left upper eyelid. The patient reported no history of trauma. A provisional diagnosis of chalazion was established, and an excisional biopsy was performed. Histopathologically, the lesion was lined with a stratified squamous epithelium, with a corrugated epithelial surface showing abrupt keratinization without keratohyalin granules, and compact keratinous-appearing material in the cystic lumen. The diagnosis was IKC. No signs of recurrence were observed after one year of follow-up. It is essential to accurately diagnose IKC and distinguish it from chalazion and epidermal inclusion cysts, because IKC requires complete surgical excision and can exhibit multiple recurrences if not properly removed.

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“…With an understanding of ocular embryology, Williams et al reviewed the published literature on torpedo maculopathy and speculate that this lesion develops from a congenital nerve fiber layer-driven mechanism 2 . Similarly, meticulous synthesis of the clinical and pathologic features of corneal opacification in acquired corneal subepithelial hypertrophy by Al-Rajhi et al 3 , of the various etiologies of tarsal cysts by Al Rubaian et al 4 , and of challenging inflammatory juvenile conjunctival melanocytic nevi by Nebot et al 5 will expand our understanding of these diseases.…”

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confidence: 99%