Tartaric Acid New Synthetic Derivatives Antibacterial Activity against the Phytopathogenic Pseudomonas syringae

Abstract

Antimicrobial resistance is one of the most pressing issues of our time, according to WHO's reports over the past several years. And day by day the further aggravation of the mentioned problem is being caused by increase in antibiotic usage values in various scopes of mankind activity. That is why, the search of novel ecologically safe alternatives of classical antibiotic therapy against pathogen microorganisms is very significant direction of research world around. And it is important not only in case of human pathogens, but also for opportunistic pathogenic microorganisms, pathogens of plants and animals that have a significant impact on public health and agriculture.During this research, 4 new synthetic derivatives of natural antimicrobial compoundtartaric acid, were elaborated at the laboratory of new agrarian pesticides creation and the quality control of National Polytechnic University of Armenia (NPUA). Their biological activity and biodegradation potential were tested on different soil microorganisms, such as like various strains of phytopathogenic Pseudomonas syringae, from The National Collection of Microorganisms of Microbe Depository Centre (MDC), "Armbiotechnology" Scientific & Production Center (SPC), National Academy of Sciences (NAS), Republic of Armenia (RA).According to results, complex salts of tartaric acid are effective as the prospective and a comparably ecologically safe alternative for combating antimicrobial resistance in this plant pathogen P. syringae. Besides, the obtained substances are effective against the other opportunistic pathogenic representatives of same genera, such as like P. aeruginosa and P. fluorescens. Moreover, the mentioned compounds are biodegradable by soil non-pathogenic P. chlororaphis.

The impact of organic preparations on the growth, development and efficiency indicators of some newly produced spiked cereals (barley, emmer, triticale)

“…Apart from being seeds disinfectant, this preparation also serves as a plants growth stimulant and is a combination of wine treatment solution and additives (tartaric amino acid components) providing improved properties [27].…”

“…Though, there is a large number of microelements in the soil (zinc, manganese, iron, copper, etc.) their solubility and availability for plants is very low [15], and the scarcity of different microelements in crops is manifested by very different from each other symptoms [16].…”

Ways of obtaining organic products from several bread crops (barley, emmer and wheat)

“…At the same time, it also has the best properties of a plant growth promoter, significantly increasing the degree of effective plant tillering in bread crops. The above mentioned valuable properties of "Complex -Co" organic preparation were presented in our previous report [10].…”