TAS/TVS versus histopathological diagnosis in abnormal uterine bleeding: A comparative study

Abstract

Background: Any uterine bleeding outside the normal volume, duration, regularity or frequency is considered abnormal uterine bleeding. Objectives: This study was conducted to evaluate the efficacy of TAS/TVS and histopathological findings in AUB patients. Methods: A prospective study was done on 101 females of various age groups attending the Department of obstetrics and gynaecology over a period of 1 year with a clinical diagnosis of AUB. Each patient irrespective of the baseline investigations and sonography findings were subjected to premenstrual dilatation and curettage as well as hysteroscopy accordingly hence endometrial tissue obtained was subjected to histopathological examination. Result: In our present study the most recurring clinical uterine lesion noted was myoma in about 34.16%, followed by Adenomyosis in about 33.54%. Endometrial polyp was noted at 21.11% and endometrial carcinoma was in 8.69%. Cervical polyp and cervical carcinoma found in 1.24%. The sensitivity and specificity of sonography for Diagnosing Polyp as compared to HPE was 52.77% and 98.46% while positive predictive value and negative predictive value were 95.00 % and 79.01% respectively. Conclusion:Transabdominal or transvaginal ultrasound is low cost primary modality for screening and should include as a first line screening method. Though the investigation and management of AUB among the non-gravid women was confusing, histopathological diagnosis proved to be the gold standard.