Taste alterations and oral discomfort in patients receiving chemotherapy

Larsen, Anne Kathrine; Thomsen, Christine; Sanden, Mathilde; Skadhauge, Lotte Boa; Anker, Camilla Bundgaard; Mortensen, Martin; Bredie, Wender L.P.

doi:10.1007/s00520-021-06316-4

Cited by 21 publications

(21 citation statements)

References 47 publications

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“…This study showed a higher rate of chemosensory dysfunction than a previous study which showed the prevalence of self-reported chemosensory dysfunction was 32.5%, and the prevalence of alteration of only smell and taste sense was 24.6% and 26.9%, respectively 21. In the previous study, symptoms were self-reported, while in our study the modified CiTAS and SNOT-22 scales were used, which provide sensitive recognition of symptoms 32. The difference is also attributed to the fact that most of the participants (98%) are aged less than 60 years old, with a mean age of 41±4 years.…”

Section: Discussioncontrasting

confidence: 47%

“… 21 In the previous study, symptoms were self-reported, while in our study the modified CiTAS and SNOT-22 scales were used, which provide sensitive recognition of symptoms. 32 The difference is also attributed to the fact that most of the participants (98%) are aged less than 60 years old, with a mean age of 41±4 years. Some other studies reported that alteration of smell and taste was significantly more common among younger individuals.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of taste and smell dysfunction in mild and asymptomatic COVID-19 patients during Omicron prevalent period in Shanghai, China: a cross-sectional survey study

et al. 2023

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ObjectivesCOVID-19, which is caused by SARS-CoV-2, is a severe threat to human health and the economy globally. This study aimed to investigate the prevalence of taste and/or smell dysfunction and associated risk factors in mild and asymptomatic patients with Omicron infection in Shanghai, China.DesignThis was a questionnaire-based cross-sectional study.SettingCOVID-19 patients at the makeshift hospital in the Shanghai World Expo Exhibition and Convention Centre were recruited from March to April 2022.ParticipantsIn total, 686 COVID-19-infected patients who were defined as mild or asymptomatic cases according to the diagnostic criteria of New Coronavirus Pneumonia Prevention and Control Programme ninth edition (National Health Commission of China, 2022) were enrolled.MeasuresData to investigate taste and smell loss and to characterise other symptoms were collected by the modified Chemotherapy-induced Taste Alteration Scale and Sino-Nasal Outcome Test-22 questionnaires. The risk factors for the severity of taste/smell dysfunction were analysed by binary logistic regression models.Results379 males (379/686, 55.2%) and 307 females (307/686, 44.8%) completed the questionnaires to record recent changes in taste and smell ability. A total of 302 patients (44%) had chemosensory dysfunction with Omicron infection, of which 22.7% (156/686) suffered from both taste and smell dysfunction. In addition, cough (60.2%), expectoration (40.5%), fever (33.2%) and sore throat (32.5%) were common symptoms during Omicron infection. The quality-of-life-related indicators were negatively associated with participants’ self-reported taste and smell dysfunction.ConclusionsThe prevalence of taste or/and smell dysfunction in patients with Omicron infections was 44%. Individuals with chemosensory dysfunction had significantly higher rates of various upper respiratory influenza-like symptoms, xerostomia and bad breath. Moreover, smell dysfunction was a risk factor for the prevalence of taste dysfunction in patients with Omicron infection.Trial registration numberChiCTR 2200059097.

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Section: Discussioncontrasting

confidence: 47%

Section: Discussionmentioning

confidence: 99%

Prevalence of taste and smell dysfunction in mild and asymptomatic COVID-19 patients during Omicron prevalent period in Shanghai, China: a cross-sectional survey study

et al. 2023

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“…In the study that was carried out by Celik et al (n=196), it was found that patients experienced moderate levels of taste changes, as well as moderate levels of phantogeusia and parageusia among types of taste change (25). In other studies using CiTAS and examining taste changes in different types of cancer, CiTAS subscale scores have usually been reported in the range of 1-3 (7,26,27). In addition to the direct physiological effects of chemotherapy, other symptoms of the disease itself and the adverse effects of chemotherapy also affect the sensation of taste.…”

Section: Discussionmentioning

confidence: 99%

The Effects of Taste Changes on the Quality of Life of Patients Receiving Chemotherapy Treatment

DOLU>

Menekli

2023

Medical Records

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Abstract Objective: The aim of this study is to determine the effect of taste changes on quality of life in cancer patients taking chemotherapy. Material and method: This descriptive study was conducted between January 2020 and September 2020 with cancer patients receiving chemotherapy in the inpatient and outpatient unit of a university hospital. The sample consisted of 466 cancer patients who met the inclusion criteria and received the same treatment at the same university hospital. Data were collected using the Introductory Information Form, the European Organization for Cancer Research and Treatment Quality of Life Scale Version 3 (EORTC QLQ-C30 Version 3.0), and the Chemotherapy-Induced Taste Change Scale (CiTAS). Results: While the mean total score of EORTC QLQ-C30 was 62.97±13.31, the mean total score of CiTAS was found to be 40.43±17.84. Statistically significant correlations were found between total scores of EORTC QLQ-C30 and CiTAS scales and sub-dimension scores (p

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“…Bu çalışmada da hastalar orta şiddette tat değişikliği yaşarken, tat değişikliğine bağlı rahatsızlığı da orta şiddette deneyimlediği belirlenmiştir. CiTAS ölçeğinin kullanılarak farklı kanser tip tanısı olan hastalarda tat değişikliğinin değerlendirildiği çalışmalarda genellikle hastaların CiTAS ölçeğinin alt boyut puan skorları 1 ile 3 arasında değişiklik göstermiştir (29)(30)(31). Diğer çalışma sonuçlarından da kemoterapi alan kanserli hastalarda tat değişikliği niteliğinin farklı yoğunlukta ve farklı sıklıkta olabildiği anlaşılmaktadır (9, 23,24).…”

Section: Verilerin Toplanmasıunclassified

Kemoterapi Alan Akciğer Kanserli Hastalarda Tat Değişiklerinin Değerlendirilmesi

Özkan¹,

Eroğlu²

2022

STED / Sürekli Tıp Eğitimi Dergisi

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Bu çalışma kemoterapi alan akciğer kanserli hastaların deneyimledikleri tat değişikliklerini değerlendirmek amacıyla planlanmıştır. Gereç ve Yöntem: Kesitsel olarak planlanan bu çalışma İstanbul ilinde bir eğitim araştırma hastanesinin kemoterapi ünitesinde Aralık 2020-Mayıs 2021 tarihleri arasında yapılmıştır. Araştırma verileri tanımlayıcı bilgi formu ve Kemoterapiye Bağlı Tat Alma Değişikliği Ölçeğiyle toplanmıştır. Bulgular: Akciğer kanserli hastaların % 62.3'ünün tat değişikliği deneyimlediği, % 68.6' sının tat değişikliğine yönelik sağlık profesyonellerinden bilgi almadığı, %35.8'inin tat değişimini metalik tat olarak tanımladığı, %35.8'inin tat değişikliğiyle baş etme yöntemi olarak yemekleri soğuk yedikleri saptanmıştır. Hastaların CiTAS ölçeğinin temel tatlarda azalma alt boyut ortalamasının 2.49±1.39; rahatsızlık alt boyut ortalamasının ve paraguzi and fantoguzi alt boyut ortalamasının 2.48±1.35; genel tat değişikliği alt boyut ortalamasının ise 2.49±1.36 olduğu belirlenmiştir. Sonuç: Çalışmada kemoterapi alan akciğer kanserli hastaların yarıdan fazlasının tat değişikliklerini deneyimlediği, orta şiddette tat duyusunda değişiklik ve rahatsızlık yaşadıkları ve en çok tanımladıkları tat değişikliğinin metalik tat olduğu belirlenmiştir. Bu sonuçlar doğrultusunda sağlık profesyonellerinin akciğer kanserli hastaların yaşadıkları tat değişikliklerini farkında olması, niteliğini ve şiddetini değerlendirmesi, takip etmesi ve buna yönelik gerektiğinde interdisipliner yaklaşımla önleyici ve tedavi edici girişimlerde bulunması önerilmektedir.

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Taste alterations and oral discomfort in patients receiving chemotherapy

Cited by 21 publications

References 47 publications

Prevalence of taste and smell dysfunction in mild and asymptomatic COVID-19 patients during Omicron prevalent period in Shanghai, China: a cross-sectional survey study

Prevalence of taste and smell dysfunction in mild and asymptomatic COVID-19 patients during Omicron prevalent period in Shanghai, China: a cross-sectional survey study

The Effects of Taste Changes on the Quality of Life of Patients Receiving Chemotherapy Treatment

Kemoterapi Alan Akciğer Kanserli Hastalarda Tat Değişiklerinin Değerlendirilmesi

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