Taurodontism in dental genetics

Roomaney, Imaan Amina; Beighton, Peter

doi:10.1038/s41405-021-00081-6

Cited by 24 publications

(44 citation statements)

References 47 publications

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“…Increased bleeding during pulp chamber trepanation may be mistaken for perforation 1 ; however, due to root shortening and the apical displacement of the pulpal chamber, floor perforations can occur. 3,12,17 The complexity of the root canal system makes its instrumentation almost impossible. Because of this, the authors recommend the use of sodium hypochlorite to dissolve the remaining pulp that cannot be removed with instruments.…”

Section: Resultsmentioning

confidence: 99%

Clinical implications of a diagnosis of taurodontism: A literature review

Pach¹,

Regulski²,

Tomczyk³

et al. 2022

Adv Clin Exp Med

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Taurodontism is a morphological anomaly involving multirooted teeth that is characterized by a vertical shift of the pulp chamber and shortening of the roots. The literature was analyzed to determine the impact of a diagnosis of taurodontism on dental treatment. A total of 85 full-text publications from the years 2005-2021 were analyzed and 20 publications were included in this research. The endodontic treatment of a taurodont tooth is challenging due to the apical displacement of the pulpal chamber floor and the incorrect configuration of the root canal system, or the presence of additional canals. In terms of prosthetics, the use of taurodont teeth as abutments is not recommended as they lack stability due to shorter roots. The extraction of taurodont teeth can be complicated due to an apical shift of the root furcation. In periodontology, taurodont teeth can have a better prognosis as there is less chance of furcation involvement. From an orthodontic point of view, it is important to note that taurodont teeth are not sufficiently embedded in the alveolus and have a greater tendency for root resorption. With regard to genetic diseases, it has been reported that this anomaly can exist as an isolated feature. However, the majority of authors agree that taurodontism is associated with conditions such as Down syndrome, Klinefelter syndrome, cleft lip and palate, hypodontia, amelogenesis imperfecta, and others. From a clinical standpoint, it is very important to diagnose taurodontism before treatment. A diagnosis of taurodontism can be important in the early diagnosis of malformations that commonly occur with this condition.

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Section: Resultsmentioning

confidence: 99%

Clinical implications of a diagnosis of taurodontism: A literature review

Pach¹,

Regulski²,

Tomczyk³

et al. 2022

Adv Clin Exp Med

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“…There are several syndromes where taurodontism has been identified like osteogenesis imperfecta, Torg–Winchester syndrome, TDO, cleft lip, and palate. 73 TDO syndrome is associated with DLX3 gene mutations, which are also associated with amelogenesis imperfecta hypoplastic hypomaturation with taurodontism. 74 Taurodontism is also seen in Torg–Winchester syndrome, which is associated with matrix metalloproteinase 2 (MMP2) genetic mutations.…”

Section: Genes Involved In Dental Anomaliesmentioning

confidence: 99%

The Human Genetics of Dental Anomalies

Khan

Ahmed²,

Neela

et al. 2022

Glob Med Genet

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The development of tooth is a highly complex procedure and mastered by specific genetic programs. Genetic alterations, environmental factors, and developmental timing can disturb the execution of these programs, and result in various dental anomalies like hypodontia/oligodontia, and supernumerary teeth, which are commonly seen in our clinical practice. Advances in molecular research enabled the identification of various genes involved in the pathogenesis of dental anomalies. In the near future, it will help provide a more accurate diagnosis and biological-based treatment for these anomalies. In this article, we present the molecular phenomenon of tooth development and the genetics of various dental anomalies.

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“…Hamner et al (1964) proposed that taurodontism would result from a failure in the epithelial diaphragm of Hertwig's Sheath. Some of the possible explanations for the etiopathogenesis of taurodontism: (a) an exceptional developmental delay; (b) delay in calcification of the floor of the pulp chamber; (c) odontoblastic deficiency and (d) alteration in Hertwig's epithelial sheath and (e) delay or incomplete union of the horizontal flaps of the epithelial diaphragm of Hertwig's sheath (Chetty et al, 2021).…”

Section: Detailing Of Dental Anomaliesmentioning

confidence: 99%

“…In 1928, Shaw classified taurodontism as: hypo, meso, and hyper taurodontism, based on level of displacement of the apical wall of the pulp cavity (Shaw, 1928). Taurodontism is observed both as an isolated occurrence and as a part of a syndrome, which include Tricho dento osseous syndrome, Klinefelter syndrome, ectodermal dysplasia, and several other genetic conditions (Chetty et al, 2021; Hegde et al, 2013). This anomaly can occur unilaterally or bilaterally; it can reach both dentitions, although it is more common in permanent dentition.…”

Section: Detailing Of Dental Anomaliesmentioning

confidence: 99%

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Dental anomalies in non‐syndromic orofacial clefts: A clinical approach

et al. 2022

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Orofacial clefts (OC) represent some of the most common congenital malformations and affect multiple structures in the craniofacial region. There are a wide range of morphological OC types within the spectrum of both non‐syndromic OC (NSOC) and syndromic OC, including cleft lip (CL), cleft lip and palate, (CLP), and cleft palate (CP). Here, we describe the most frequent dental anomalies seen in the permanent dentition of individuals with NSOC, comparing them between the three main cleft types (CL, CLP, and CP). We present these findings from the perspective of prevalence relating to each anomaly, as well as the clinical characteristics and potential impact on the rehabilitation process. The investigation of dental anomalies associated with NSOC is important, helping to expand the phenotypic characterization of NSOC, improve the initial diagnostics, and establish appropriate rehabilitation and counseling.

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Taurodontism in dental genetics

Cited by 24 publications

References 47 publications

Clinical implications of a diagnosis of taurodontism: A literature review

Clinical implications of a diagnosis of taurodontism: A literature review

The Human Genetics of Dental Anomalies

Dental anomalies in non‐syndromic orofacial clefts: A clinical approach

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