Taxonomy and species concepts in the genus
            <i>Salmonella</i>
            .

Sanderson, K E; Nair, S. Gopalakrishnan; Barrow, Paul; Methner, U.

doi:10.1079/9781845939021.0001

Cited by 12 publications

(10 citation statements)

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“…However, it has also been reported that SA S d may occasionally cause rhinitis or chronic nasal inflammation [10, 11], orchitis [12], or aborted foetuses [4]. As these properties deviate from the classical characteristics of host-restricted, host-adapted or ubiquitous serovars [13], the term sheep associated serovar [6] appears most appropriate to characterise serovar 61: k: 1, 5, (7).…”

Section: Introductionmentioning

confidence: 99%

Occurrence and characterisation of Salmonella enterica subspecies diarizonae serovar 61: k: 1, 5, (7) in sheep in the federal state of Thuringia, Germany

Methner

Moog

2018

BMC Vet Res

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BackgroundThe occurrence of Salmonella enterica subspecies diarizonae serovar 61: k: 1, 5, (7) (SASd) and other Salmonella organisms in sheep in the German federal state of Thuringia was examined for the first time. Pooled faecal samples from 90 flocks located in this state were monitored.ResultsOnly SASd was detected in 74 (82.2%) out of the 90 sheep herds, other Salmonella serovars were not identified. A positive correlation was found between the flock size and the detection probability of SASd. Despite the agent’s high prevalence, clinical symptoms of a disease exclusively due to SASd have not been observed. The SASd strains were characterised by macrorestriction analysis, antimicrobial testing and the biochemical profile. All strains were sensitive to 13 out of 14 antimicrobial substances and resistant to only sulfamethoxazole. The high number of macrorestriction groups of SASd strains indicated a low clonality of the serovar.ConclusionsData from sheep derived foods and public health data in Germany strongly suggest that the significance of SASd for public health is considerably lower than that of serovars belonging to Salmonella enterica subspecies enterica. For this reason and because of the low disease-causing potential of SASd in sheep, it is worthwile to consider a reduction in ongoing activities from combating to monitoring serovar 61: k: 1, 5, (7) in the sheep population.

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Section: Introductionmentioning

confidence: 99%

Occurrence and characterisation of Salmonella enterica subspecies diarizonae serovar 61: k: 1, 5, (7) in sheep in the federal state of Thuringia, Germany

Methner

Moog

2018

BMC Vet Res

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“…More than 2,500 Salmonella serovars have so far been identified, while 99% of human and animal infections are caused solely by one subspecies, Salmonella enterica subsp. enterica ( S. enterica ) ( 3 ). With regard to human disease, S. enterica has traditionally been divided into a small number of human-restricted invasive typhoidal Salmonella and thousands of non-typhoidal Salmonella (NTS) ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

O-Serotype Conversion in Salmonella Typhimurium Induces Protective Immune Responses against Invasive Non-Typhoidal Salmonella Infections

Liu

Luo

et al. 2017

Front. Immunol.

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Salmonella infections remain a big problem worldwide, causing enteric fever by Salmonella Typhi (or Paratyphi) or self-limiting gastroenteritis by non-typhoidal Salmonella (NTS) in healthy individuals. NTS may become invasive and cause septicemia in elderly or immuno-compromised individuals, leading to high mortality and morbidity. No vaccines are currently available for preventing NTS infection in human. As these invasive NTS are restricted to several O-antigen serogroups including B1, D1, C1, and C2, O-antigen polysaccharide is believed to be a good target for vaccine development. In this study, a strategy of O-serotype conversion was investigated to develop live attenuated S. Typhimurium vaccines against the major serovars of NTS infections. The immunodominant O4 serotype of S. Typhimurium was converted into O9, O7, and O8 serotypes through unmarked chromosomal deletion–insertion mutations. O-serotype conversion was confirmed by LPS silver staining and western blotting. All O-serotype conversion mutations were successfully introduced into the live attenuated S. Typhimurium vaccine S738 (Δcrp Δcya) to evaluate their immunogenicity in mice model. The vaccine candidates induced high amounts of heterologous O-polysaccharide-specific functional IgG responses. Vaccinated mice survived a challenge of 100 times the 50% lethality dose (LD50) of wild-type S. Typhimurium. Protective efficacy against heterologous virulent Salmonella challenges was highly O-serotype related. Furthermore, broad-spectrum protection against S. Typhimurium, S. Enteritidis, and S. Choleraesuis was observed by co-vaccination of O9 and O7 O-serotype-converted vaccine candidates. This study highlights the strategy of expressing heterologous O-polysaccharides via genetic engineering in developing live attenuated S. Typhimurium vaccines against NTS infections.

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“…The subspecies enterica (I) groups the majority (1547, 60%) of serovars that affect human and domestic animals (Dekker & Frank, 2015;Grimont & Weill, 2007;OIE, 2012), and those serovars are classified as typhoidal and nontyphoidal Salmonella (NTS) (Sanderson & Nair, 2013). Contaminated meat and poultry products such as commercial table eggs and raw chicken meat constitute the main sources of S. enterica (Ricke & Calo, 2015).…”

Section: Introductionmentioning

confidence: 99%

Phenotypic and Genotypic Antibiotic Resistance of Salmonella from Chicken Carcasses Marketed at Ibague, Colombia

Velez

Rodríguez

García

2017

Rev. Bras. Cienc. Avic.

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Taxonomy and species concepts in the genus Salmonella .

Abstract: The taxonomy, nomenclature, phylogenetics and molecular epidemiology of Salmonella spp. are described.

Cited by 12 publications

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Occurrence and characterisation of Salmonella enterica subspecies diarizonae serovar 61: k: 1, 5, (7) in sheep in the federal state of Thuringia, Germany

Occurrence and characterisation of Salmonella enterica subspecies diarizonae serovar 61: k: 1, 5, (7) in sheep in the federal state of Thuringia, Germany

O-Serotype Conversion in Salmonella Typhimurium Induces Protective Immune Responses against Invasive Non-Typhoidal Salmonella Infections

Phenotypic and Genotypic Antibiotic Resistance of Salmonella from Chicken Carcasses Marketed at Ibague, Colombia

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