With the development of wireless technology, many TCP-based HTTP applications are running slow, especially under the wireless environment. This paper first analyzes the causes of this situation, and then discusses the advantages of Google's experimental QUIC protocol in wireless transmission and finds that QUIC is easy to extend and deploy, providing a good framework for personalized optimization. This paper applies the QUIC framework and presents a QUIC optimization algorithm for the VPN or LAN scenarios, which mainly improves the congestion algorithm on the basis of QUIC. Through simulation tests, it is found in the wireless environment with high latency and high packet loss rate, the QUICMING-based HTTP applications perform significantly better than those based on TCP, SPDY and default QUIC.