TCT-152 Impact of Body Surface Area on Outcomes in Patients With Lower Extremity Peripheral Arterial Disease

Abstract

Background: The long-term outcomes for endovascular intervention (EVI) in Asian people with critical limb ischemia (CLI) are still uncertain. This study was designed to assess the feasibility and patient outcomes after EVI for Taiwanese patients with CLI. Methods: From June 2005 to December 2011, 270 patients underwent EVI for CLI of 333 limbs. Primary patency (PP), assisted primary patency (AP), limb salvage, sustained clinical success (SCS), secondary sustained clinical success (SSCS) and survival were assessed using Kaplan-Meier analysis. Results: The procedural success rate was 94% and 53% of legs required stent implantation to optimize the procedural result. The periprocedural mortality and major complications rate within 30 days was 0.6% and 6.9%, respectively. During the mean follow-up time of 27Ϯ20 months (1-77), 64 patients died and 25 legs underwent major amputation with a total of 93% follow-up rate. 81% of patients with tissue loss had wound healing at 6 months and 75% of patients can be ambulatory with or without assist device at 1 year. Overall survival rate of CLI patients at 1, 3, 5 year was 88%, 70% and 61%. The rates of free from major and any amputation at 1 year were 90% and 78%, respectively and can be maintained to 5 years. The PP and AP at 1, 3, 5 year was 58%, 37%, 31% and 79%, 61% and 52%, respectively. The SCS and SSCS were 65%, 46%, 38% and 80%, 64%, 55% at 1, 3,5 years, respectively. Conclusions: EVI proved to be a safe and feasible procedure for CLI patients. Sustained limb salvage and clinical success can be achieved with an active surveillance program and prompt assisted intervention during long-term follow-up.

Association Between Body Surface Area and Outcomes After Percutaneous Coronary Intervention

“…14 Obesity is a well-established risk factor for cardiovascular disease, 15 hence findings of better prognosis in obese patients than in normal-weight patients who are treated for heart failure, coronary disease and peripheral artery disease led to the term "obesity paradox." [16][17][18][19][20] This suggests that obesity is a marker for a different unidentified factor that confers favorable cardiovascular outcomes. A positive correlation has been shown between body surface area (BSA), BMI and coronary artery size.…”