Sustainable development and sustainability are two widely used umbrella concepts, both "brilliantly ambiguous." Many fields of study, including engineering, business, the humanities, and the sciences offer opportunities for instructors to connect content with sustainability. As the central science, chemistry is surely one of them. This paper issues a call for action to chemistry instructors to build stronger connections in the college chemistry curriculum to the local, regional and global challenges that we face on our planet.These challenges, multi-faceted and multi-disciplinary, include providing clean energy, protecting the environment and stewarding its resources, employing wise agricultural practices to supply food, and insuring clean water and clean air to those in all communities. As a chemical concept, the carbon cycle connects to challenges such as these. It is presented as a possibility for building stronger connections to sustainability in the curriculum.