Team Approach: Metal Hypersensitivity in Total Joint Arthroplasty

Abstract

UpdateThis article was updated on February 10, 2023, because of a previous error. On page 1, the title that had read “Team Approach” with the subtitle “Metal Hypersensitivity in Total Joint Arthroplasty” now reads “Team Approach: Metal Hypersensitivity in Total Joint Arthroplasty” with no subtitle.An erratum has been published: JBJS Rev. 2023;11(2):e22.00157ER.As total joint arthroplasty volume continues to grow nationwide, more uncommon complications such as metal implant hypersensitivity are reported with greater frequency in the literature.Metal hypersensitivity is a challenging diagnosis given the potentially vague symptomology. It should be considered a diagnosis of exclusion, necessitating careful consideration of other potential etiologies of a failing implant before arriving at the final diagnosis of metal hypersensitivity.Patients can experience substantial morbidity from implant rejection and in severe, refractory cases may even require revision arthroplasty and conversion to a hypoallergenic implant.Given the complex nature of the condition, successful treatment of metal hypersensitivity to orthopaedic implants is best achieved through the use of a multidisciplinary, team-based approach. Immunologists, radiologists, and infectious disease physicians as well as orthopaedic surgeons and mechanical engineers are all vital in appropriate diagnosis and treatment of the condition.