Interdisciplinary research is useful when answers to complex social problems are sought. As a method is praised for the multiple benefits that provides in the enlargement of scientific knowledge and interdisciplinary collaboration. The EMPOWERED Project is a paradigm of interdisciplinary research. This Project aimed to utilize IoT technology for supporting the independent living for older people with chronic diseases. The contribution of interdisciplinary research to the enhancement of self-management strategies and the autonomous living of this population group was highlighted throughout the four stages of the Project and reflected in its final results. Strategies for eliminating barriers to interdisciplinary research are recommended.