Tear Strength Analysis of MDX4-4210 and A-2186 Silicones with Different Intrinsic Pigments Incorporated by Mechanical and Industrial Methods

Goiato, Marcelo Coelho; Nóbrega, Adhara Smith; Silva, Emily Vivianne Freitas da; Bertoz, André Pinheiro de Magalhães; Sônego, Mariana Vilela; Neto, Clóvis Lamartine de Moraes Melo

doi:10.1155/2019/2573095

Cited by 7 publications

(74 citation statements)

References 18 publications

(47 reference statements)

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“…7,14,22 The extrinsic factors like ultraviolet radiation, daily handling, temperature, air pollution, water absorption, and adsorption can also cause degradation of a silicone. [1][2][3]5,7,8,10,[13][14][15][16][17]22 According to Goiato et al 9 and Mancuso et al, 15 the use of 1,008 hours of accelerated aging (in vitro) corresponds to 1 year of constant use of a silicone prosthesis by the patient. 9,15 Therefore, if a silicone prosthesis generally has a maximum clinical durability of 1 year, 2,[4][5][6][7]10,13,15 aging for 1,008 hours (in vitro) is sufficient to simulate a clinical situation.…”

Section: Discussionmentioning

confidence: 99%

“…5,7,9,13,14,16,17 The intrinsic opacifier (ZnO) corresponded to 2% of the silicone weight. 3 The silicone was manipulated at 23 ± 2°C with a relative humidity 5,[7][8][9]13,14,16,17 of 50 ± 10%. 14,16,17 The base and catalyst paste were mixed according to the manufacturer's recommendations until the paste becomes homogeneous.…”

Section: Preparation Of Samplesmentioning

confidence: 99%

“…24 The samples were subjected to alternating periods of ultraviolet B light (UVB-313 lamps, 40 Watts, Equilam) and condensation of distilled water under the conditions of heat and 100% humidity. 3,5,7,9,[13][14][15][16][17] Each aging cycle was performed for 12 hours. In the first 8 hours, the temperature was maintained at 60 ± 3°C, and the ultraviolet B light was imputed onto the samples.…”

Section: Color Stability and Shore A Hardness Testsmentioning

confidence: 99%

“…In the first 8 hours, the temperature was maintained at 60 ± 3°C, and the ultraviolet B light was imputed onto the samples. 3,5,7,9,[13][14][15][16][17] In the last 4 hours, the temperature was maintained at 45 ± 3°C and a condensation period occurred without ultraviolet B light. 3,5,7,9,[13][14][15][16][17] This process simulated the deterioration caused by rainwater, dew, and ultraviolet light from the sun.…”

Section: Color Stability and Shore A Hardness Testsmentioning

confidence: 99%

“…3,5,7,9,[13][14][15][16][17] In the last 4 hours, the temperature was maintained at 45 ± 3°C and a condensation period occurred without ultraviolet B light. 3,5,7,9,[13][14][15][16][17] This process simulated the deterioration caused by rainwater, dew, and ultraviolet light from the sun. 3,5,7,9,[14][15][16][17] The aging was performed for a total of 1,008 hours.…”

Section: Color Stability and Shore A Hardness Testsmentioning

confidence: 99%

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Analysis of Color and Hardness of a Medical Silicone with Extrinsic Pigmentation after Accelerated Aging

et al. 2020

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Objective The aim of this study is to evaluate the color alteration and shore A hardness of a medical silicone with extrinsic pigmentation, before and after accelerated aging. Materials and Methods Twenty samples (Silastic Q7–4735) were made with an intrinsic pigmentation. This intrinsic pigmentation was composed of a pink pigment (H-109-P, Factor II) and an opacifier (ZnO). All samples had standardized dimensions (45-mm diameter and 2-mm thickness). Half of the 20 samples manufactured subsequently received an extrinsic pigment (Tan FE–215, Factor II). Therefore, two groups were created (n = 10): Group 1, group with intrinsic pigmentation and without extrinsic pigmentation (control) and Group 2, group with intrinsic and extrinsic pigmentation. Samples were submitted to color and Shore A hardness tests, before and after 1,008 hours of aging. Statistical Analysis Color alteration data were submitted to Student’s t-test (α = 0.05). Shore A hardness data were submitted to two-way analysis of variance and Tukey test (α = 0.05). Results The incorporation of the extrinsic pigment on the silicone did not affect its color (ΔE) when the two groups were compared (p = 0.232). Regarding the hardness test, the interaction between group and period did not interfere with the hardness results(p=0.599). However, the period factor showed that there was a reduction in the hardness of the silicone after aging (p < 0.05). Conclusion In this study, all the hardness and color results of the silicone used were clinically acceptable, regardless of the presence of extrinsic pigmentation.

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Section: Discussionmentioning

confidence: 99%

Section: Preparation Of Samplesmentioning

confidence: 99%

Section: Color Stability and Shore A Hardness Testsmentioning

confidence: 99%

Section: Color Stability and Shore A Hardness Testsmentioning

confidence: 99%

Section: Color Stability and Shore A Hardness Testsmentioning

confidence: 99%

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Analysis of Color and Hardness of a Medical Silicone with Extrinsic Pigmentation after Accelerated Aging

et al. 2020

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Facile Modification of Medical-Grade Silicone for Antimicrobial Effectiveness and Biocompatibility: A Potential Therapeutic Strategy against Bacterial Biofilms

Wynne,

Zolotarskaya,

Jarrell

et al. 2023

ACS Appl. Mater. Interfaces

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A one-step modification of biomedical silicone tubing with N,N-dimethyltetradecylamine, C14, results in a composition designated WinGard-1 (WG-1, 1.1 wt % C14). A surface-active silicon-amine phase (SAP) is proposed to account for increased wettability and increased surface charge. To understand the mechanism of antimicrobial effectiveness, several procedures were employed to detect whether C14 leaching occurred. An immersion-growth (IG) test was developed that required knowing the bacterial Minimum Inhibitory Concentrations (MICs) and Minimum Biocidal Concentrations (MBCs). The C14 MIC and MBC for Gm– uropathogenic E. coli (UPEC), commonly associated with catheter-associated urinary tract infections (CAUTI), were 10 and 20 μg/mL, respectively. After prior immersion of WG-1 silicone segments in a growth medium from 1 to 28 d, the IG test for the medium showed normal growth for UPEC over 24 h, indicating that the concentration of C14 must be less than the MIC, 10 μg/mL. GC-MS and studies of the medium inside and outside a dialysis bag containing WG-1 silicone segments supported de minimis leaching. Consequently, a 5 log UPEC reduction (99.999% kill) in 24 h using the shake flask test (ASTM E2149) cannot be due to leaching and is ascribed to contact kill. Interestingly, although the MBC was greater than 100 μg/mL for Pseudomonas aeruginosa, WG-1 silicone affected an 80% reduction via a 24 h shake flask test. For other bacteria and Candida albicans , greater than 99.9% shake flask kill may be understood by proposing increased wettability and concentration of charge illustrated in the TOC. De minimis leaching places WG-1 silicone at an advantage over conventional anti-infectives that rely on leaching of an antibiotic or heavy metals such as silver. The facile process for preparation of WG-1 silicone combined with biocidal effectiveness comprises progress toward the goals of device designation from the FDA for WG-1 and clearance.

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The Effect of Nano Zinc Oxide Particles on Color Stability of MDX4-4210 Silicone Prostheses

Charoenkijkajorn

Sanohkan

2020

Eur J Dent

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Objective This article aimed to study the effect of different concentrations of nano zinc oxide particles on the color change of MDX4–4210 facial silicone elastomer after artificial aging. Materials and Methods Silicone specimens (N = 150) were fabricated by incorporating intrinsic pigments and divided into three groups—white, yellow, and red, each group consisting of 50 specimens (n = 50). In each color, specimens were subdivided into five subgroups according to the quantity of zinc oxide nanoparticles (0, 0.5, 1.0, 1.5, and 2.0% weight), where the 0% weight served as the control in each group. All specimens were then subjected to artificial aging using an accelerated aging machine chamber for 12, 24, 48, and 72 hours. L*a*b* values of specimens were noted after a different aging period by a spectrophotometer and ∆E* was calculated. Statistical Analysis Two-way repeated analysis of variance (ANOVA) was done to examine the effects under test conditions (concentration and aging time) of each color group. Then color, concentration, and the aging period were subjected to three-way repeated ANOVA to investigate the effects of different colors and concentrations on ∆E*. Bonferroni’s test was performed to identify differences between groups. The significant level was at p = 0.05. Results The control group showed significantly higher ∆E* values than the test groups. The 1.5% test group showed significantly lower ∆E* compared with the others. The 0.5 to 2.0% of nano zinc oxide significantly decreased the color change of the silicone elastomer (p < 0.05), but there were no significant differences among groups. Conclusions Incorporation of 1.5% of nano zinc oxide can improve the color stability of silicone prosthesis (MDX4–4210).

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Tear Strength Analysis of MDX4-4210 and A-2186 Silicones with Different Intrinsic Pigments Incorporated by Mechanical and Industrial Methods

Cited by 7 publications

References 18 publications

Analysis of Color and Hardness of a Medical Silicone with Extrinsic Pigmentation after Accelerated Aging

Analysis of Color and Hardness of a Medical Silicone with Extrinsic Pigmentation after Accelerated Aging

Facile Modification of Medical-Grade Silicone for Antimicrobial Effectiveness and Biocompatibility: A Potential Therapeutic Strategy against Bacterial Biofilms

The Effect of Nano Zinc Oxide Particles on Color Stability of MDX4-4210 Silicone Prostheses

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