Technical Note: Construction of heterogeneous head phantom for quality control in stereotactic radiosurgery

Najafi, Mahdi; Teimouri, Javad; Shirazi, Alireza; Geraily, Ghazaleh; Esfahani, Mahbod; Shafaei, M.

doi:10.1002/mp.12496

Cited by 6 publications

(3 citation statements)

References 9 publications

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“…The heterogeneous brain phantom model presented by Najafi et al [26] has polytetrafluoroethylene and methyl methacrylate as a bone and soft tissue and the phantom was tested for stereotactic radiosurgery. Joachimowicz et al [27] proposed the use of TX-100 and salted water for the preparation of brain phantom for the frequency range of 0.5-6 GHz band.…”

Section: Brain Phantomsmentioning

confidence: 99%

Realistic 3D Phantoms for Validation of Microwave Sensing in Health Monitoring Applications

Särestöniemi,

Singh,

Dessai

et al. 2024

Preprint

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The development of new medical monitoring applications requires precise modeling of the human body effects as well as simulating and emulating realistic scenarios and conditions. The first aim of this paper is to develop realistic and adjustable human body 3D emulation platforms which could be used for evaluating emerging microwave-based medical monitoring/sensing applications such as the detection of brain tumors, strokes, breast cancers as well as for capsule endoscopy studies. The new phantom recipes are developed for microwave ranges for the realistic shaped phantom molds. The second aim is to validate the feasibility and reliability of the phantoms for practical scenarios with electromagnetic simulations using tissue layer models and biomedical antennas. The third aim is to investigate the impact of the water temperature in the phantom cooking phase on the dielectric properties of the stabilized phantom. The evaluations show that the dielectric properties of the developed phantoms correspond closely to those of real human tissue. The error in dielectric properties varies between 0.5-8%. In the practical scenario simulations, the differences obtained with phantoms-based simulations in S21 parameters are 0.1-13dB. However, the differences are smaller in the frequency ranges targeted for medical applications.

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Section: Brain Phantomsmentioning

confidence: 99%

Realistic 3D Phantoms for Validation of Microwave Sensing in Health Monitoring Applications

Särestöniemi,

Singh,

Dessai

et al. 2024

Preprint

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show abstract

“…The heterogeneous brain-phantom model presented by Najafi et al [ 26 ] used polytetrafluoroethylene and methyl methacrylate as bone and soft tissue, and the phantom was tested for stereotactic radiosurgery. Joachimowicz et al [ 27 ] proposed the use of TX-100 and salted water for the preparation of a brain phantom for a frequency range of 0.5–6 GHz.…”

Section: Introductionmentioning

confidence: 99%

Realistic 3D Phantoms for Validation of Microwave Sensing in Health Monitoring Applications

Särestöniemi,

Singh,

Dessai

et al. 2024

Sensors

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The development of new medical-monitoring applications requires precise modeling of effects on the human body as well as the simulation and the emulation of realistic scenarios and conditions. The first aim of this paper is to develop realistic and adjustable 3D human-body emulation platforms that could be used for evaluating emerging microwave-based medical monitoring/sensing applications such as the detection of brain tumors, strokes, and breast cancers, as well as for capsule endoscopy studies. New phantom recipes are developed for microwave ranges for phantom molds with realistic shapes. The second aim is to validate the feasibility and reliability of using the phantoms for practical scenarios with electromagnetic simulations using tissue-layer models and biomedical antennas. The third aim is to investigate the impact of the water temperature in the phantom-cooking phase on the dielectric properties of the stabilized phantom. The evaluations show that the dielectric properties of the developed phantoms correspond closely to those of real human tissue. The error in dielectric properties varies between 0.5–8%. In the practical-scenario simulations, the differences obtained with phantoms-based simulations in S21 parameters are 0.1–13 dB. However, the differences are smaller in the frequency ranges used for medical applications.

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“…Water-equivalent materials (with rED *1, such as thermoplastics and silicones) mimic the response of soft tissues (e.g., brain matter), 15,16 whereas bone-equivalent materials (rED *1.5-2, typical of highdensity polymers, such as polytetrafluoroethylene [PTFE]) mimic that of hard parts. 17,18 The design and fabrication of cerebral vascular phantoms using additive manufacturing for neurosurgery have already been reported in the literature. 13,[19][20][21][22] The most representative examples are mainly related to surgical aid applications (e.g., aneurysm clipping 20,23 ) as well as to diagnosis, 24,25 blood circulation analysis, 26,27 and patients' information purposes.…”

Section: Introductionmentioning

confidence: 99%

Additive Fabrication of a Vascular 3D Phantom for Stereotactic Radiosurgery of Arteriovenous Malformations

Legnani

Gallo

Pezzotta

et al. 2021

3D Printing and Additive Manufacturing

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In this study, an efficient methodology for manufacturing a realistic three-dimensional (3D) cerebrovascular phantom resembling a brain arteriovenous malformation (AVM) for applications in stereotactic radiosurgery is presented. The AVM vascular structure was 3D reconstructed from brain computed tomography (CT) data acquired from a patient. For the phantom fabrication, stereolithography was used to produce the AVM model and combined with silicone casting to mimic the brain parenchyma surrounding the vascular structure. This model was made with tissues-equivalent materials for radiology. The hollow vascular system of the phantom was filled with a contrast agent usually employed on patients for CT scans. The radiological response of the phantom was tested and compared with the one of the clinical case. The constructed model demonstrated to be a very accurate physical representation of the AVM and its vasculature and good morphological consistency was observed between the model and the patient-specific source anatomy. These results suggest that the proposed method has potential to be used to fabricate patient-specific phantoms for neurovascular radiosurgery applications and medical research.

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Technical Note: Construction of heterogeneous head phantom for quality control in stereotactic radiosurgery

Cited by 6 publications

References 9 publications

Realistic 3D Phantoms for Validation of Microwave Sensing in Health Monitoring Applications

Realistic 3D Phantoms for Validation of Microwave Sensing in Health Monitoring Applications

Realistic 3D Phantoms for Validation of Microwave Sensing in Health Monitoring Applications

Additive Fabrication of a Vascular 3D Phantom for Stereotactic Radiosurgery of Arteriovenous Malformations

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