Technique of Intraperitoneal Chemotherapy Using Veress Needle in Patients With Ovarian Cancer

Ramarajapalli, Manjunath Laxmayya; Kilara, Nalini; Subramanyam, Murali; Rao, Nitin A R

doi:10.1097/igc.0b013e318228f441

Cited by 6 publications

(6 citation statements)

References 5 publications

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“…With aseptic precautions and after infiltration of local anaesthesia, Veress needle was inserted intraperitoneally in the left or right spinoumbilical line (the midline is not a suitable site because of previous surgical scar and probable adhesions) and its position confirmed by standard tests. For full details of the procedure of Veress needle instillation please refer [2]. Initially, 1 L of normal saline, then cisplatin or paclitaxel mixed in normal saline, and finally, 0.5 L/1 L of normal saline heated as explained above were instilled intraperitoneally by gravitational force (Figure 2).…”

Section: Techniquementioning

confidence: 99%

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Technique of Post- Operative HIPEC (Hyperthermic Intraperitoneal Chemotherapy) using Veress Needle and IVFluid Warmer In Patients With Epithelial Ovarian Cancer

Ramarajapalli¹

2017

OGIJ

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Objective: Favourable oncological outcomes have been reported with the use of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with advanced epithelial ovarian cancer (EOC). However one course of intraoperative HIPEC is complex procedure. We present the simple postoperative technique of HIPEC using Veress needle and IVFluid warmer in patients with epithelial ovarian cancer. Materials and Methods:14 patients with EOC received 74 cycles of HIPEC postoperatively. Intraperitoneal instillation of chemotherapeutic drugs was done using Veress needle and for warming the fluid IVFluid warmer device like HOTLINE Fluid warmer or enFlow were used. Results:After CRS 14 patients with EOC received 74 cycles of HIPEC postoperatively. 11 (78.57%) patients completed all 6 cycles of planned HIPEC. Complications related the procedure like pain, tenderness at procedure site, cellulitis etc. were managed conservatively.Conclusion: HIPEC using Veress needle and IVFluid warmer is simple technique for 6 cycles of hyperthermic IP therapy.

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Section: Techniquementioning

confidence: 99%

“…Veress needle has been used to instill IP chemotherapy to decrease catheter related complications. The advantages of using Veress Needle for Intra Peritoneal instillation have been explained [2]. We describe the technique of postoperative HIPEC using Veress Needle and IVFluid warmer in patients with epithelial ovarian carcinoma (EOC).…”

Section: Introductionmentioning

confidence: 99%

Technique of Post- Operative HIPEC (Hyperthermic Intraperitoneal Chemotherapy) using Veress Needle and IVFluid Warmer In Patients With Epithelial Ovarian Cancer

Ramarajapalli¹

2017

OGIJ

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“…The advantages of using Veress Needle for Intra Peritoneal instillation have been explained [2]. We describe the technique of postoperative HIPEC using Veress Needle and IVFluid warmer in patients with epithelial ovarian carcinoma (EOC).…”

Section: Introductionmentioning

confidence: 99%

“…For full details of the procedure of Veress needle instillation please refer [2]. Initially, 1 L of normal saline, then cisplatin or paclitaxel mixed in normal saline, and finally, 0.5 L/1 L of normal saline heated as explained above were instilled intraperitoneally by gravitational force (Figure 2).…”

Section: Techniquementioning

confidence: 99%

Technique of Post- Operative HIPEC (Hyperthermic Intraperitoneal Chemotherapy) using Veress Needle and IVFluid Warmer In Patients With Epithelial Ovarian Cancer

Ramarajapalli¹

2017

OGIJ

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“…Limitations of IP chemotherapy include not only the high toxicity profile and consequent low completion rate, but also inconvenient administration using an IP catheter. Several researchers have therefore introduced new IP chemotherapy techniques and various protocols modified from GOG 172 [9]. In this study we aimed to assess the efficacy of single-dose IP cisplatin administered immediately after completion of cytoreductive surgery in advanced stage of EOC, focusing on the effect on survival and chemotherapeutic toxicity.…”

Section: Introductionmentioning

confidence: 99%

Survival outcomes and toxicity of intraoperative intraperitoneal chemotherapy in advanced epithelial ovarian cancer

et al. 2014

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ObjectiveTo assess the effect of single-dose cisplatin intraperitoneally administered during cytoreductive surgery in advanced epithelial ovarian cancer.MethodsData from patients who underwent surgical management followed by intravenous (IV) chemotherapy for stage III epithelial ovarian cancer from 2003 to 2012 were retrospectively reviewed. Subjects were divided into intraperitoneal (IP) and no-intraperitoneal (NIP) groups according to the administration of IP cisplatin 100 mg during the staging surgery. Clinical results such as survival outcomes and chemotherapeutic toxicity were compared between the two groups.ResultsThirty-seven patients in the IP group and 26 in the NIP group were identified. There were no significant differences between the two groups in basic characteristics such as age, histology, and surgical procedures. After the surgery with or without IP chemotherapy, there was no difference in the rate of either hematologic or gastrointestinal toxicity or in the rate of incompletion of following IV chemotherapy. Tumor recurrence occurred in 67.6% (25 patients) of IP group and 57.7% (15 patients) of NIP group (P=0.423) during the mean follow-up period of 37 months. The 3-year disease free-survival rate was 39.9% in the IP group and 35.8% in the NIP group, and the relative risk of recurrence was 0.864 (95% confidence interval, 0.447-1.673; P=0.665) in the IP group as compared with the NIP group.ConclusionIP chemotherapy with single-dose cisplatin during cytoreductive surgery is safe and feasible with little chemotherapeutic toxicity in advanced epithelial ovarian cancer, but no distinct improvement in survival could be demonstrated in the present study.

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Technique of Intraperitoneal Chemotherapy Using Veress Needle in Patients With Ovarian Cancer

Cited by 6 publications

References 5 publications

Technique of Post- Operative HIPEC (Hyperthermic Intraperitoneal Chemotherapy) using Veress Needle and IVFluid Warmer In Patients With Epithelial Ovarian Cancer

Technique of Post- Operative HIPEC (Hyperthermic Intraperitoneal Chemotherapy) using Veress Needle and IVFluid Warmer In Patients With Epithelial Ovarian Cancer

Technique of Post- Operative HIPEC (Hyperthermic Intraperitoneal Chemotherapy) using Veress Needle and IVFluid Warmer In Patients With Epithelial Ovarian Cancer

Survival outcomes and toxicity of intraoperative intraperitoneal chemotherapy in advanced epithelial ovarian cancer

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