Techniques and Results—Penumbra Aspiration Catheter

Kreusch, Andreas S.; Psychogios, Marios‐Nikos; Knauth, Michael

doi:10.1053/j.tvir.2011.12.007

Cited by 5 publications

(5 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The 4 Fr catheter used in these experiments is at the lower range of sizes used for intracranial suction thrombectomy (internal diameter 0.89–1.63 mm) in clinical practice,20 23 24 but appropriate for the size of the experimental vessel. The diameter of the catheter has no bearing on the conclusions of this work as the results are qualitative rather than quantitative.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow

Lally

Soorani

Woo

et al. 2015

J NeuroIntervent Surg

View full text Add to dashboard Cite

Background: Mechanical thrombectomy with stenttriever devices is associated with significantly better outcomes than thrombolysis alone in the treatment of acute ischaemic stroke. Thrombus aspiration achieves high patency rates, but clinical outcomes are variable. The aim of this study was to examine the effect of different suction conditions on perfusate flow during aspiration thrombectomy. Results:The mathematical model predicted that in a patent vessel perfusate is drawn from upstream of the catheter tip, while in an occluded system perfusate is drawn from the vessel proximal to the device tip, with no traction on the occlusion distal of the tip. The in-vitro experiments confirmed the predictions of this model. In the occluded vessel aspiration had no effect on the thrombus unless the tip of the catheter was in direct contact with the thrombus. Conclusion:These experiments suggest that aspiration is only effective if the catheter tip is in direct contact with the thrombus. If the catheter tip is not in contact with the thrombus aspirate is drawn from the vessels proximal of the occlusion. This could affect collateral flow in vivo.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The size of the catheter was chosen to match the size of the target vessel (2.4 mm) using recommendations for catheter size for currently used catheters in vivo 20 21…”

Section: Methodsmentioning

confidence: 99%

In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow

Lally

Soorani

Woo

et al. 2015

J NeuroIntervent Surg

View full text Add to dashboard Cite

show abstract

“…A currently FDA-approved proximal mechanical retriever for the treatment of ischemic stroke is Penumbra (Penumbra Inc., Alameda, CA). Penumbra uses a separator at the tip of the instrument combined with aspiration to disrupt and remove the occlusive clot using an axial push force [18][19][20][21]. Geunther et al [22] propose a different designed proximal mechanical retriever in combination with a distal balloon and [23,24] a proximal expandable cylindrical tube cutter in combination with a distal balloon for axial clot resection and removal, respectively (Fig.…”

Section: A) Low-speed Impact Forcementioning

confidence: 99%

Treating Total Occlusions: Applying Force for Recanalization

Sakes

Regar

Dankelman

et al. 2016

IEEE Rev. Biomed. Eng.

View full text Add to dashboard Cite

show abstract

“…While several recent studies have shown that both the Penumbra aspiration system and FST are safe and efficacious in the treatment of ischemic stroke, they have also alluded to the fact that FST represents a quicker and more flexible treatment option 1 3 4. Because of its minimalistic design, FST provides advantages in preparation time and time to revascularization.…”

Section: Introductionmentioning

confidence: 99%

“…Because of its minimalistic design, FST provides advantages in preparation time and time to revascularization. Additionally, if FST fails, it can be quickly and easily converted to the Penumbra system 1 3…”

Section: Introductionmentioning

confidence: 99%