Techniques for thyroid FNA: A synopsis of the National Cancer Institute Thyroid Fine‐Needle Aspiration State of the Science Conference

Pitman, Martha B.; Abele, John S.; Ali, Syed Z.; Duick, Dan; Elsheikh, Tarik M.; Jeffrey, R. Brooke; Powers, Celeste N.; Randolph, Gregory W.; Renshaw, Andrew A.; Scoutt, Leslie M.

doi:10.1002/dc.20829

Cited by 206 publications

(159 citation statements)

References 106 publications

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“…30 Many issues related to thyroid There was 1 false-negative case of papillary carcinoma with extensive lymphocytic thyroiditis that was caused by a specimen sampling error. There were no false-positive cases.…”

Section: Discussionmentioning

confidence: 99%

Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules

Zhang

Ivanovic

Nemcek

et al. 2008

Cancer

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N‐vinylcarbazole (NVC) was polymerized by 13X zeolite alone in melt (65°C) or in toluene (110°C) and a poly(N‐vinylcarbazole) (PNVC)‐13X composite was isolated. Composites of polypyrrole (PPY) and polyaniline(PANI) with 13X zeolite were prepared via polymerization of the respective monomers in the presence of dispersion of 13X zeolite in water (CuCl2 oxidant) and in CHCl3 (FeCl3 oxidant) at an ambient temperature. The composites were characterized by Fourier transform infrared analyses. Scanning electron microscopic analyses of various composites indicated the formation of lumpy aggregates of irregular sizes distinct from the morphology of unmodified 13X zeolite. X‐ray diffraction analysis revealed some typical differences between the various composites, depending upon the nature of the polymer incorporated. Thermogravimetric analyses revealed the stability order as: 13X‐zeolite > polymer‐13X‐zeolite > polymer. PNVC‐13X composite was essentially a nonconductor, while PPY‐13X and PANI‐13X composites showed direct current conductivity in the order of 10−4 S/cm in either system. However, the conductivity of PNVC‐ 13X composite could be improved to 10−5 and 10−6 S/cm by loading PPY and PANI, respectively. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 101: 913–921, 2006

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Section: Discussionmentioning

confidence: 99%

Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules

Zhang

Ivanovic

Nemcek

et al. 2008

Cancer

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“…Hemorrhagic complications after US-FNA were more frequent when using thicker needles (6,8,10). In this study, hemorrhagic complications were significantly lower with 25 G than 22 G or 21 G needles.…”

Section: Discussionmentioning

confidence: 44%

“…Informed consent for US-FNA was obtained from before each procedure. US-FNA was performed according to recommendations for thyroid nodules (3,8,11,12,24,25). Factors related to US-FNA procedure, such as diameter of the needle, the pass number of the needle per one nodule, whether performing fluid aspiration just before US-FNA, application of the suction during US-FNA were assessed to reveal the relationship with hemorrhagic complication.…”

Section: Us-guided Fna Biopsymentioning

confidence: 99%

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Contributory Factors to Hemorrhage After Ultrasound-Guided Fine Needle Aspiration of Thyroid Nodules with an Emphasis on Patients Taking Antithrombotic or Anticoagulant Medications

et al. 2018

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Background: Thyroid nodules are a common clinical problem and ultrasound-guided fine needle aspiration (US-FNA) biopsy is widely used for evaluation of thyroid nodules. However, few studies have addressed the contributing factors to hemorrhage after US-FNA of thyroid nodules. Objectives: To assess the contributory factors related to patient characteristics, ultrasound (US) features of the thyroid nodules, and the US-FNA procedures to affect hemorrhage complications after US-FNA of thyroid nodules. Methods: Between March 2014 and April 2015, 366 consecutive patients who underwent US-FNA of thyroid nodules were enrolled in this retrospective study. The characteristics of hematomas, including the location, maximum size, and clinical course, were assessed. The relationships between hematomas and factors related to the medical characteristics of patients, US characteristics of the nodules, and FNA procedural factors were analyzed. Results: Data on 365 nodules in 321 patients who underwent US-FNA of thyroid nodules were analyzed. Minor hemorrhagic complications developed in 14 (3.8%) of the 365 nodules. There were no statistically significant differences between patients taking or not taking an anticoagulant or antithrombotic (P = 0.270). Factors related to increased risk of hematoma were male sex (P = 0.031), larger maximum size (P = 0.002), a cystic or predominantly cystic nodule (P < 0.0001), a probable benign nodule (P < 0.0001), thicker needle size (P < 0.0001), and a greater number of the needle passes (P = 0.005). Conclusions: US-FNA can be performed safely even in patients taking anticoagulant or antithrombotic agents. Factors related to hemorrhagic complications are male sex, larger nodules, cystic or predominantly cystic nodules, probably benign nodules, thicker needles and a greater number of needle passes.

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“…Tanulmányunkból az FNAC-diagnózisokat követő kórszövettani vizsgálattal a 10 mm-nél kisebb, úgyneve-zett microcarcinomákat, továbbá a pajzsmirigy-carcinomák lokális recidíváit, a nyirokcsomó áttéteit, valamint egyéb malignomáknak a pajzsmirigybe adott metasztázi-sait és a non-Hodgkin-lymphomákat kihagytuk. A mintavételeket radiológus vagy citopatológus szakorvosok a Pitman és mtsai [20] A citohisztológiai korrelációt a 3. táblázat mutatja. A citológiailag I., nem diagnosztikus csoportból 40 beteget megoperáltak, és szövettani vizsgálattal 37 eset struma nodosának, 3 papillaris microcarcinomának (tumornagyság 10 mm alatti) bizonyult.…”

Section: Betegek éS Módszerunclassified

Pajzsmirigygöbök vékonytű-aspirációs citológiai vizsgálata. A Bethesda-rendszer (2008) minőségbiztosítása

Bak¹,

Ilona²,

Nyári

et al. 2015

Orvosi Hetilap

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Bevezetés: A pajzsmirigybetegségek diagnosztikájának módszertana rendkívül széles, magába foglalja a fi zikális, radiológiai, ultrahang-, izotóp-, laboratóriumi és a vékonytű-technikás aspirációs citológiai vizsgálatokat. Célkitűzés: A szerzők célja a pajzsmirigygöbök aspirációs citológiai gyors, azonnal adott diagnózisainak követése, citohisztológi-ai összehasonlítása, illetve minőségbiztosítása volt. Módszer: 1348 beteg pajzsmirigy-aspirációs vizsgálatát végezték el. A citológiai diagnózisokat a Bethesda System for Reporting Thyroid Cytopathology (2008) On-site fi ne-needle aspiration cytology of thyroid nodules Quality assurance of the Bethesda System for Reporting Thyroid Cytopathology (2008)Introduction: The methods available for the diagnosis of thyroid nodules include physical examination, imaging, laboratory and fi ne-needle aspiration cytology tests. Aim: The aim of this study was to determine the quality assurance of fi ne-needle aspiration cytology of thyroid nodules. Method: Cytology results were rated to 6 categories according to the Bethesda System for Reporting Thyroid Cytopathology (2008) (I. nondiagnostic; II. benign; III. atypia of undetermined signifi cance; IV. follicular neoplasia; V. suspicious for malignancy; VI. malignant). All cytology reports were compared with the fi nal histology diagnosis. Results: A total of 1384 patient with thyroid nodule underwent fi ne-needle aspiration biopsy cytology. Smears were classifi ed I. inadequate in 214 (15.9%); II. benign 986; III. atypical 56; IV. follicular neoplasm 41; V. suspicious for malignancy 18; VI. malignant 33 cases. Two hundred and twenty seven (16.8%) of the cases were operated and histologically verifi ed. The positive predictive value in the benign category was 98.25% and in the malignant 88.46%. The sensitivity of the follicular neoplasm was 66.67%. Conclusion:The results suggest that fi ne-needle aspiration cytology of thyroid nodules using the Bethesda System for Reporting Thyroid Cytopathology has a high diagnostic accuracy. The auditing values of the results meet the proposed threshold values.

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Techniques for thyroid FNA: A synopsis of the National Cancer Institute Thyroid Fine‐Needle Aspiration State of the Science Conference

Cited by 206 publications

References 106 publications

Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules

Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules

Contributory Factors to Hemorrhage After Ultrasound-Guided Fine Needle Aspiration of Thyroid Nodules with an Emphasis on Patients Taking Antithrombotic or Anticoagulant Medications

Pajzsmirigygöbök vékonytű-aspirációs citológiai vizsgálata. A Bethesda-rendszer (2008) minőségbiztosítása

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