Technologies of regenerative medicine as a method of treatment of male infertility: literature review

Abstract

The problem of infertility has recently become quite widespread all over the world, having a negative impact on couples themselves and society as a whole. The male factor of infertility accounts for about 50% of cases, in this regard, a large number of studies conducted are aimed at finding new methods of treating this disease. However, the accepted modern methods of treatment, including assisted reproductive technologies, are currently not effective enough. Recently, much attention has been devoted to the use of regenerative medicine technologies in the treatment of diseases of the reproductive system of men and women due to its significant potential. This review presents existing experimental and clinical studies that studied the effect, safety and efficacy of stem cells of various kinds of origin, induced pluripotent stem cells, exosomes, spermatogonial stem cells, platelet rich plasma in the treatment of various types of male infertility.