Environmental conditions may have a significant impact on the construction and operation of underground works, and sudden changes in environmental conditions may lead to underground engineering damage. Considering the Yellow River crossing tunnel on Huanggang Road in Jinan as an example, this paper analyzes the mechanical performance of the lining of the shield tunnel with an external diameter of 16.8 m, which faces the challenge of large variable loads in operation stage, such as deep riverbed erosion and deposition, large-scale heightening of river embankment, seasonal changes in groundwater level, and key technologies for improving the resilience of tunnel structure are proposed accordingly. The results can not only assist in the construction of the super-large-diameter shield tunnel project in Jinan City but also provide technical support for other shield tunnel projects crossing rivers, lakes, and seas.