Tedavi Dozunda Klomipramin Kullanımına Bağlı Gelişen Ventriküler Taşikardi Olgusu

Abstract

A 57-year-old housewife was admitted to the emergency department with a 2-hour history of palpitations and acute dyspnea. Upon detailed examination of her medical history, it was found that she had been suffering from tachycardia attacks lasting 10-15 minutes for six months and been receiving anti-depressant therapy for ten years. Her electrocardiogram (ECG) indicated ventricular tachycardia (VT), which rapidly changed to sinus rhythm with cardioversion. Clomipramine therapy was ceased as QTc was calculated as 600 ms. At the initial 3-day follow-up, the rhythm of the patient who had three times attacks was converted to sinus rhythm with cardioversion. Later, the QTc value of the patient who had no VT attack was evaluated as 420 ms in her ECG which was analyzed at the end of the first week of her hospitalization. The patient was discharged from the hospital on the fifteenth day of her hospitalization. We present a case of VT from use of clomipramine at therapeutic dosage.