Monolithic integration of III-V nanowires on silicon platforms has been regarded as a promising building block for many on-chip optoelectronic, nanophotonic, and electronic applications. Although great advances have been made from fundamental material engineering to realizing functional devices, one of the remaining challenges for on-chip applications is that the growth direction of nanowires on Si(001) substrates is difficult to control. Here, we propose and demonstrate catalystfree selective-area epitaxy of nanowires on ( 001)-oriented silicon-on-insulator (SOI) substrates with the nanowires aligned to desired directions. This is enabled by exposing {111} planes on (001) substrates using wet chemical etching, followed by growing nanowires on the exposed planes. We demonstrate the formation of nanowire array-based bottom-up photonic crystal cavities on SOI(001) and their coupling to silicon waveguides and grating couplers, which support the feasibility for onchip photonic applications. The proposed method of integrating position-and orientationcontrollable nanowires on Si(001) provides a new degree of freedom in combining functional and ultracompact III-V devices with mature silicon platforms.