Telescoping of landmark events associated with drinking: a gender comparison.

Randall, Carrie L.; Roberts, James S.; Boca, Frances K. Del; Carroll, Kathleen M.; Connors, Gerard J.; Mattson, Margaret E.

doi:10.15288/jsa.1999.60.252

Cited by 288 publications

(226 citation statements)

References 21 publications

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“…Adult men are 2 to 3 times more likely than women to have a drug abuse/dependence disorder, but this current gender difference may reflect differences in opportunity, rather than vulnerability to drug use [125,126]. If one looks at rate of escalation of drug use, however, women tend to increase their rate of consumption of alcohol, marijuana, opioids and cocaine more rapidly than do men [19,54,82,86,99]. Furthermore, once addicted to a drug, women can find it more difficult to quit than men do.…”

Section: Sex Differences In Drug Abuse In Humansmentioning

confidence: 99%

Sex differences in drug abuse

Becker

2008

Frontiers in Neuroendocrinology

867

688

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Sex differences are present for all of the phases of drug abuse (initiation, escalation of use, addiction, and relapse following abstinence). While there are some differences among specific classes of abused drugs, the general pattern of sex differences is the same for all drugs of abuse. Females begin regularly self-administering licit and illicit drugs of abuse at lower doses than do males, use escalates more rapidly to addiction, and females are at greater risk for relapse following abstinence. In this review, sex differences in drug abuse are discussed for humans and in animal models. The possible neuroendocrine mechanisms mediating these sex differences are discussed.

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Section: Sex Differences In Drug Abuse In Humansmentioning

confidence: 99%

Sex differences in drug abuse

Becker

2008

Frontiers in Neuroendocrinology

867

688

View full text Add to dashboard Cite

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“…For substance use disorders, including alcohol, opioid, and cannabis dependence, females advance more rapidly from use to regular use to first treatment episode than do their male counterparts (Dawson, 1996;Hernandez-Avila et al, 2004;Johnson et al, 2005;Orford and Keddie, 1985;Piazza et al, 1989;Randall et al, 1999). In addition, when they enter treatment, in spite of fewer years of use and smaller quantities of substances used, their substance abuse symptom severity is generally equivalent to that of males (Hernandez-Avila et al, 2004;Piazza et al, 1989;Randall et al, 1999). Even with fewer years of substance use, at treatment entry, females average more medical, psychiatric, and adverse social consequences of their substance use disorders than males.…”

Section: Introductionmentioning

confidence: 99%

Substance abuse treatment entry, retention, and outcome in women: A review of the literature

Greenfield

Brooks

Gordon

et al. 2007

Drug and Alcohol Dependence

890

782

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This paper reviews the literature examining characteristics associated with treatment outcome in women with substance use disorders. A search of the English language literature from 1975 to 2005 using Medline and PsycInfo databases found 280 relevant articles. Ninety percent of the studies investigating gender differences in substance abuse treatment outcomes were published since 1990, and of those, over 40% were published since the year 2000. Only 11.8% of these studies were randomized clinical trials. A convergence of evidence suggests that women with substance use disorders are less likely, over the lifetime, to enter treatment compared to their male counterparts. Once in treatment, however, gender is not a significant predictor of treatment retention, completion, or outcome. Gender-specific predictors of outcome do exist, however, and individual characteristics and treatment approaches can differentially affect outcomes by gender. While women-only treatment is not necessarily more effective than mixed-gender treatment, some greater effectiveness has been demonstrated by treatments that address problems more common to substance-abusing women or that are designed for specific subgroups of this population. There is a need to develop and test effective treatments for specific subgroups such as older women with substance use disorders, as well as those with co-occurring substance use and psychiatric disorders such as eating disorders. Future research on effectiveness and cost-effectiveness of gender-specific versus standard treatments, as well as identification of the characteristics of women and men who can benefit from mixed-gender versus single-gender treatments, would advance the field.

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“…For example, a retrospective study of 419 treatment-seeking women enrolled in a multisite alcohol treatment matching study found that while women on average began getting drunk and experiencing problems later than men, they progressed more quickly than men from first getting drunk to first problems (Randall, et al, 1999). This "telescoping effect" has been documented by several other studies as well (Schuckit, et al, 1995;Johnson, et al, 2005).…”

Section: Introductionmentioning

confidence: 81%

The 14-year course of alcoholism in a community sample: Do men and women differ?

Edens

Glowinski

Grazier

et al. 2008

Drug and Alcohol Dependence

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Objective-To investigate the course of alcoholism in males and females in a 14-year followup of persons with DSM-III alcoholism compared to very heavy drinkers and unaffected controls in a community sample.Methods-Case-control study based on data from the 1997 Health Services Use and Cost study, a 14-year followup survey of 442 individuals who participated in 2 waves of the 1981-1983 St. Louis Epidemiologic Catchment Area study. Cases met criteria for DSM-III alcohol abuse (AA) or dependence (AD) at both waves of the ECA: "Two-times Alcohol Use Disorder Positives (ECA 2t-AUDPs)." Two comparison groups were frequency matched to 2t-AUDPs: 1) ECA Very Heavy Drinkers/One-time Alcohol Use Disorder Positives (ECA VHD/1t-AUDPs) and 2) ECA Alcoholunaffecteds. Lifetime and past year alcohol use disorders, patterns of drinking and recovery among males and females are reported.Results-84.6% of 2t-AUDPs again met lifetime DSM-III criteria at 14-year followup. At followup, only 9.3% male 2t-AUDPs and 20.7% female 2t-AUDPs met past year DSM-IV AUD criteria. Past year drinking patterns, however, revealed higher rates of DSM-IV AA or AD, problemor risk drinking among 2t-AUDPs (61.7%) compared to both ECA VHD/1t-AUDPs (41.2%) and ECA Alcohol-unaffecteds (22.1%).Conclusions-In a community sample, the rate of past year DSM-IV alcohol dependence was lower among male 2t-AUDPs than females, though both groups showed past year rates substantially lower than lifetime rates. However, less than half of ECA 2t-AUDPs exhibited low-risk or abstinent alcohol use behaviors, indicating that while remission from diagnosis is common, clinical relevance persists.

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Telescoping of landmark events associated with drinking: a gender comparison.

Cited by 288 publications

References 21 publications

Sex differences in drug abuse

Sex differences in drug abuse

Substance abuse treatment entry, retention, and outcome in women: A review of the literature

The 14-year course of alcoholism in a community sample: Do men and women differ?

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