[1] We present a 3-D P wave velocity model of the crust and shallowest mantle under the Italian region, that includes a revised Moho depth map, obtained by regional seismic travel time tomography. We invert 191,850 P n and P g wave arrival times from 6850 earthquakes that occurred within the region from 1988 to 2007, recorded by 264 permanent seismic stations. We adopt a high-resolution linear B-spline model representation, with 0.1 horizontal and 2 km vertical grid spacing, and an accurate finite-difference forward calculation scheme. Our nonlinear iterative inversion process uses the recent European reference 3-D crustal model EPcrust as a priori information. Our resulting model shows two arcs of relatively low velocity in the crust running along both the Alps and the Apennines, underlying the collision belts between plates. Beneath the Western Alps we detect the presence of the Ivrea body, denoted by a strong high P wave velocity anomaly. We also map the Moho discontinuity resulting from the inversion, imaged as the relatively sharp transition between crust and mantle, where P wave velocity steps up to values larger than 8 km/s. This simple condition yields an image quite in agreement with previous studies that use explicit representations for the discontinuity. We find a complex lithospheric structure characterized by shallower Moho close by the Tyrrhenian Sea, intermediate depth along the Adriatic coast, and deepest Moho under the two mountain belts. Gualtieri, L., P. Serretti, and A. Morelli (2014), Finite-difference P wave travel time seismic tomography of the crust and uppermost mantle in the Italian region, Geochem. Geophys. Geosyst., 15,[69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85][86][87][88]