Telesurgery

Tang, Jennifer

doi:10.15173/m.v1i2.590

Cited by 2 publications

(3 citation statements)

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“…However, cancer cells can also use various strategies to limit and manipulate DCs activity to escape immune surveillance (Figure 3B). Various mechanisms within TME harass DCs functions, such as inhibition of differentiation [58], metabolic stress [59] and impaired handling of tumor-associated antigens (TAAs) 7 [60,61], resulting in insufficient T cell activation and, potentially, the induction of T cell tolerance to TAAs that causing immune escape. Engineering DCs vaccines to improve immunotherapy response and the development of DC-based vaccines is an active field of cancer research [62].…”

Section: Dendritic Cells (Dcs)mentioning

confidence: 99%

The Molecular and Immune Microenvironmental Landscape of Brain Metastases: Implications for Novel Treatment Options

Li¹,

Shen²,

Dong³

et al. 2023

Preprint

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Brain metastasis (BrM), involving the spread of cells from a primary tumor through the blood circulation system to the brain microvasculature, eventually progresses despite multiple treatments and remains a substantial contributor to major mortality in patients with advanced- stage cancer. Molecular signatures and immune cellular components of the tumor microenvironment (TME) are emerging as essential regulators involved in establishing an organ-specific metastasis (colonization) and therapeutic response. A comprehensive understanding of detailed characterization and the immune landscape in context of process of BrM formation will greatly expand the horizon of treatments available to target these deadly diseases. In this review, we provide a comprehensive picture of the complex interactions between tumor cells and immune cellular components participated in the BrM process. Based on this knowledge, we will discuss opportunities and challenges for therapeutic strategies against BrM.

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Section: Dendritic Cells (Dcs)mentioning

confidence: 99%

The Molecular and Immune Microenvironmental Landscape of Brain Metastases: Implications for Novel Treatment Options

Li¹,

Shen²,

Dong³

et al. 2023

Preprint

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“…Bioactive ceramics such as calcium silicate, hydroxyapatite and bioglass are established as bone replacement materials and have also been investigated as potential wound dressings or as a component of composite wound dressings. [ 21–24 ] Ceramic materials based on alumina (Al 2 O 3 ) are routinely used in orthopedic and dental implants due to their high biocompatibility and load‐bearing mechanical stability. [ 25,26 ] Various types of alumina have been used for filtration applications, including bacteria filtration with anodic aluminum oxide membranes (AAO) with nano‐scale pores based on the size exclusion principle.…”

Section: Introductionmentioning

confidence: 99%

“…[ 27 ] A foldable Al 2 O 3 ‐stabilized ZrO 2 air filter paper was developed for removing particulate matter from exhaust gases at high temperature. [ 21–24,32,33 ] However, these substrates are often mechanically rigid, highly brittle and hence not the ideal fit for developing wound dressings. Here, novel flexible ceramic textiles are suggested to be a good fit for extending the application of ceramics in wound healing.…”

Section: Introductionmentioning

confidence: 99%

Alumina Ceramic Textiles as Novel Bacteria‐Capturing Wound Dressings

Dutta,

Almeida,

Karim

et al. 2024

Adv Materials Inter

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Although antimicrobial dressings have proven to be crucial in the treatment of wounds, they may give rise to antibiotic‐resistant strains or result in the release of endotoxins after bacterial death, which in turn inhibits wound healing. This study highlights the efficacy of a novel alumina ceramic textile as dressing that utilizes the principles of bacteria capture from the wound bed and inhibition of bacterial infiltration into the wound bed to reduce the bacterial burden and to inhibit the spread of infection, without the involvement of active antimicrobial substances or functional nanoparticles. The alumina textiles are compared to commercial dressings like the non‐woven mesh Cutimed Sorbact and gauzes from LEINA WERKE and performed significantly better in capturing bacteria. They are found to be effective against both Gram‐negative Escherichia coli and Gram‐positive Bacillus subtilis and show promising results in the presence of simulated wound fluid and in artificial wound bed tests from which they can be easily lifted without leaving behind any visible residues. In summary, the alumina textiles exhibit a highly efficient bacterial binding activity, possibly due to the intrinsic material properties of their hierarchical structure including the tricot knit mesh, small fiber diameters, pronounced fiber surface microtopography, and high specific surface area.

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Telesurgery

Cited by 2 publications

References 0 publications

The Molecular and Immune Microenvironmental Landscape of Brain Metastases: Implications for Novel Treatment Options

The Molecular and Immune Microenvironmental Landscape of Brain Metastases: Implications for Novel Treatment Options

Alumina Ceramic Textiles as Novel Bacteria‐Capturing Wound Dressings

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