2017
DOI: 10.1016/j.jpsychores.2017.06.009
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Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals-preliminary findings

Abstract: Objective Leukocyte telomere length (LTL) is a biomarker of cellular aging affected by chronic stress. The relationship of LTL to the stress hormones, cortisol and catecholamines, is unclear, as are possible differences between healthy controls (HC) and individuals with Major Depressive Disorder (MDD). This small pilot study is the first to examine the relationship between cortisol, catecholamines and LTL specifically in un-medicated MDD in comparison with HC. Methods Participants included 16 un-medicated MD… Show more

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Cited by 9 publications
(1 citation statement)
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“…Hence, proper telomere maintenance is crucial for ensuring healthy cellular function and preventing age-related diseases that could endanger human life. Telomere length is a dynamic marker that reflects not only genetic predispositions [ 38 ], but can be also affected by host age [ 39 ], sex [ 40 ], hormones [ 41 , 42 ], exogenous life factors (e.g., stress [ 43 ], nutrition [ 44 , 45 ], exercise [ 46 ], obesity and weight loss [ 47 ], paternal age [ 48 ], socio-economic status [ 49 ], alcohol dependence [ 50 ], tobacco smoking [ 51 ]), and environmental exposures (e.g., air pollution [ 52 ], UV radiation [ 36 ]).…”
Section: Telomeres In Health and Diseasementioning
confidence: 99%
“…Hence, proper telomere maintenance is crucial for ensuring healthy cellular function and preventing age-related diseases that could endanger human life. Telomere length is a dynamic marker that reflects not only genetic predispositions [ 38 ], but can be also affected by host age [ 39 ], sex [ 40 ], hormones [ 41 , 42 ], exogenous life factors (e.g., stress [ 43 ], nutrition [ 44 , 45 ], exercise [ 46 ], obesity and weight loss [ 47 ], paternal age [ 48 ], socio-economic status [ 49 ], alcohol dependence [ 50 ], tobacco smoking [ 51 ]), and environmental exposures (e.g., air pollution [ 52 ], UV radiation [ 36 ]).…”
Section: Telomeres In Health and Diseasementioning
confidence: 99%