“…TCI is a 240 item true/false questionnaire measuring four dimensions of temperament (novelty seeking (NS), harm avoidance (HA), reward dependence (RD), and persistence (P)) and three dimensions of character (self-directedness (SD), cooperativeness (C), and self-transcendence (ST)), developed on the basis of a psychobiological model of personality. Although TCI has been frequently used in the studies of mood disorders Celikel et al, 2009;de Winter et al, 2007;Engstrom et al, 2004;Farmer et al, 2003;Hansenne et al, 1999;Hirano et al, 2002;Kimura et al, 2000;Loftus et al, 2008;Marijnissen et al, 2002;Matsudaira and Kitamura, 2006;Naito et al, 2000;Richter et al, 2000;, no studies to date have compared TCI score profiles of patients with unipolar and bipolar depression during their depressed states. We aimed to identify personality profiles specific to either unipolar or bipolar depression, which could aid in the were also assessed with the Structured Clinical Interview for DSM-IV by a trained psychiatrist to confirm the diagnosis.…”