Temperature increase in porcine cadaver iris during direct illumination by femtosecond laser pulses

Sun, Hui; Kurtz, Ronald M.; Mikula, Eric; Juhász, Tibor

doi:10.1016/j.jcrs.2010.09.018

Cited by 11 publications

(6 citation statements)

References 40 publications

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“…Preliminary estimates suggest that 50 to 60% of laser energy passes beyond the cornea with a potential hazard to the retina and iris. [25][26][27] A safety assessment can provide an analysis of exposure relative to established exposure limits. ANSI Z136.1-2007 series provides internationally accepted exposure limits.…”

Section: Introductionmentioning

confidence: 99%

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

et al. 2011

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Abstract.We have developed a two-dimensional computer model to predict the temperature increase of the retina during femtosecond corneal laser flap cutting. Simulating a typical clinical setting for 150-kHz iFS advanced femtosecond laser (0.8-to 1-μJ laser pulse energy and 15-s procedure time at a laser wavelength of 1053 nm), the temperature increase is 0.2• C. Calculated temperature profiles show good agreement with data obtained from ex vivo experiments using human cadaver retina. Simulation results obtained for different commercial femtosecond lasers indicate that during the laser in situ keratomileusis procedure the temperature increase of the retina is insufficient to induce damage. C 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).

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Section: Introductionmentioning

confidence: 99%

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

et al. 2011

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“…The reduced cooling by the blood flow could lead to increased intraocular temperatures [6]. Sun et al [22] stated, however, that the cumulative thermal damage did not present a safety hazard on the anterior eye in porcine cadaver. According to the retinal safety, FLACS had an additional important factor that arises from plasma absorption and bubble scattering, which significantly decreased the fraction of laser power reaching the retina under the laser beam [6].…”

Section: Discussionmentioning

confidence: 99%

Short-term effects of femtosecond laser assisted cataract surgery (FLACS) on central and peripheral cornea thickness

Pahlitzsch¹,

T²

2017

New Front Ophthalmol

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Background: To assess the alterations of the cornea thickness following femtosecond laser assisted cataract surgery (FLACS) compared to the manual phacoemulsification. Methods: Data of n=42 FLACS (66.2 years) and n=40 manual phacoemulsification (71.3 years) were analysed. The procedures were performed by LenSx Alcon and Alcon Infiniti Vision System, USA. The laser setting for performing the anterior capsulotomy (diameter 5 mm) was 4.8 μJ and 8.9 μJ for the nucleus. Following parameters were examined; corneal thickness (Pentacam, Oculus Inc., Germany) at intervals of 0.4 mm to the peripheral 8 mm zone, anterior chamber depth, intraocular pressure and number of endothelial cells (NIDEK CoLtd, Japan). The analysis was performed preoperatively, directly post femtosecond laser treatment (within 15 min) and 1 day post-surgery. Results: A significant difference was not observed in the central and peripheral corneal thickness at any location (p>0.05) in FLACS compared to manual Phaco. As a trend, the complete FLACS cohort showed an increase in the peripheral corneal thickness between 4-8 mm at 1 day postoperative. The peripheral cornea thickness was significantly increased in the female FLACS cohort (4-8 mm, p<0.05). Analysing FLACS and manual Phaco considering the AC depth range of 2.5-3.5 mm could not show significant differences between the two cohorts (p>0.05). Conclusions:The results of this study suggest that conventional laser energy levels did not have a harmful short-term impact on the cornea.

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“…The combination of femtosecond laser-assisted cataract surgery and vitrectomy has been reported to enhance the accuracy of the surgery 20 21. In a clinical situation after implantation of an IOL, the viscoelastic material is removed and the aqueous humor is replaced with a balanced saline solution at room temperature.…”

Section: Discussionmentioning

confidence: 99%

Dynamic changes of optical aberrations during restoration of optical properties of hydrophobic acrylic intraocular lens ejected through cartridge

et al. 2015

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Temperature increase in porcine cadaver iris during direct illumination by femtosecond laser pulses

Abstract: The 60 kHz commercial femtosecond laser operating with pulse energies at approximately the lower limit of the range evaluated in this study would be expected to result in a 1.2 °C temperature increase and therefore does not present a safety hazard to the iris.

Cited by 11 publications

References 40 publications

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

Short-term effects of femtosecond laser assisted cataract surgery (FLACS) on central and peripheral cornea thickness

Dynamic changes of optical aberrations during restoration of optical properties of hydrophobic acrylic intraocular lens ejected through cartridge

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