The Distributed Temperature Sensing (DTS) is used to overcome the defects of traditional production profile testing technology, and realize the real-time and accurate temperature monitoring of complex underground reservoirs. Scientific interpretation of the physical phenomena and response characteristics behind the DTS temperature data is the key to accurately obtain the real-time production status and reservoir information, and is also an important premise to realize the intelligent real-time remote control of underground production. Presently, the temperature response characteristics of the production profile for multilayered gas wells have not been clearly defined, which leads to the technical problems of DTS monitoring the production profile of such gas wells. Therefore, considering the influence of the fluid heat convection, viscous dissipation, heat conduction, and other factors involved in the process of gas porous flow, this study establishes a pressure-temperature field coupling model for the multilayered gas reservoir porous flow, programs to solve the formation temperature changes for transient testing of a multilayered gas reservoir, and analyzes the influence of the temperature response characteristics of production profile on differences between gas production and formation parameter. The gas production profile of each layer are also obtained, and the accuracy and reliability of temperature response prediction are verified by fitting the actual DTS temperature test data of an offshore-multilayered gas well. The results of this study provide ideas regarding quantitative interpretation and analysis of DTS monitoring data for production profile of multilayered gas wells.