2020
DOI: 10.1002/syst.201900053
|View full text |Cite
|
Sign up to set email alerts
|

Temperature‐Responsive Low Molecular Weight Ionic Liquid Based Gelator: An Approach to Fabricate an Anti‐Cancer Drug‐Loaded Hybrid Ionogel

Abstract: Conceptualising gelators with stimuli responsiveness is advantageous to design smart materials for emerging technologies. These gelators, if are surface active and made up of active pharmaceutical ingredients, can (i) exhibit an interesting pharmaceutical profile, (ii) be useful in drug formulations and (iii) exert direct effects on cell membranes. Herein, cetylpyridinium salicylate (CetPySal) that offers higher surface activity than its precursor surfactant, cetpylpyridinium chloride (CPCl), was synthesised. … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
29
0

Year Published

2020
2020
2024
2024

Publication Types

Select...
7
1

Relationship

2
6

Authors

Journals

citations
Cited by 24 publications
(32 citation statements)
references
References 74 publications
(111 reference statements)
2
29
0
Order By: Relevance
“… 48 For the ester-functionalized SAILs, the temperature-responsive ionogel was recently reported with different ranges of CGCs. 15 …”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“… 48 For the ester-functionalized SAILs, the temperature-responsive ionogel was recently reported with different ranges of CGCs. 15 …”
Section: Resultsmentioning
confidence: 99%
“…Among the spectrum of available surfactants, ionic surfactants have edge over others because of their ability to form well-organized discrete nano- and microaggregates such as vesicles, wormlike micelles, microtubes, lamellar sheets, and 3D fibrous gels within a single system through ease and their ability to sequester a range of molecules including biological and pharmaceutical ones that can mimic the natural systems. 10 15 In an attempt to have novel surfactant structures that have ionic liquid (IL) character, the better known as surface-active ionic liquids (SAILs) are studied for their aggregation behavior in an aqueous medium. 16 21 Traditional surfactants, although having similar molecular architectures to ILs, do not fit in this category because of their higher melting points (>100 °C).…”
Section: Introductionmentioning
confidence: 99%
“…ILBSs have been explored in various fields, including chemical synthesis and catalysis [ 165 , 166 , 167 , 168 , 169 , 170 ], drug delivery [ 171 , 172 , 173 , 174 , 175 , 176 , 177 ], biomass conversion [ 178 , 179 , 180 , 181 , 182 , 183 ], liquid crystal development [ 184 , 185 , 186 ], decontamination [ 187 , 188 , 189 , 190 , 191 , 192 , 193 ] and formation and stabilization of metal NPs [ 61 , 194 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 , 212 , 213 …”
Section: Applications Of Il-based Surfactantsmentioning
confidence: 99%
“…In a different approach, ILs can be used as alternative gelling agents in drug formulations, with interesting pharmaceutical profiles, and are able to exert direct effects on cell membranes [114]. By using ILs with surface-active behavior and an API, responsive ionogels with improved sustained release profiles of drugs could be obtained.…”
Section: Ils In the Development Of (Bio)polymer-based Drug Delivery Smentioning
confidence: 99%
“…Cetylpyridinium salicylate, for example, forms a temperature-responsive ionogel at a critical gelation concentration, capable of encapsulating in its matrix imatinib mesylate, a chemotherapeutic drug. This ionogel allows different release profiles to be obtained for the API according to the pH and temperature of the media, the release being faster at body temperature and at pH = 5 in accordance with tumoral environment [114].…”
Section: Ils In the Development Of (Bio)polymer-based Drug Delivery Smentioning
confidence: 99%