The analysis of different tillage systems impact on soil properties is essential to assist farmers with management strategies. Thus, in this study, we aimed to evaluate the soil chemical properties behavior in sugarcane cultivation under different tillage systems. One tillage system consisted in five-steps deep tillage equipment and the other, in conventional method. We calculated the soil erodibility factor, as it is associated to soil chemical loss. We quantified soil organic matter, soil chemical characteristics and availability of principal nutrients, then, compared them between treatments. There was no significant difference between soil organic matter contents from both treatments. After the five-steps deep tillage, the quantity of Boron increased, while other nutrients quantities decreased. After the conventional tillage treatment, Potassium suffered a significant decrease due to soil erosion and due to high leaching characteristics of sandy soils. The soil erodibility factor was considered of high risk, this way, farmers should not flat the terrain overmuch.