Temporal and geographical distributions of human rotavirus serotypes, 1983 to 1988

Abstract

and serotypes were determined for 907 of 1,084 clinical specimens of rotaviruses collected in various countries of Europe, North and South America, Africa, and Asia. Enhanced enzyme immunoassays based on monoclonal antibodies specific for rotavirus proteins VP6 and VP7 were used. Significant differences in the prevalent serotypes were detected from year to year in the United Kingdom and Brazil and also in different countries during the same year. Throughout the study, rotavirus serotype 1 was detected most often (53.8%), followed in frequency by serotype 2 (17.8%), serotype 3 (12.1%), serotype 4 (11.1%), and serotypes other than 1 to 4 (5.1%). No individual serotype was found to predominate consistently in any one location. In the United Kingdom, rotavirus serotypes varied in prevalence in a regular but not predictable way. We suggest that a similar epidemiology might be found in other settings. Seventeen unusual strains were detected. Of these, five strains did not react with reference monoclonal antibodies specific for subgroup I and subgroup II, but they reacted with rotavirus group A-specific polyclonal and monoclonal antibodies; four strains were of subgroup II, serotype 2, and at least one had a "long" electropherotype; two strains were of subgroup I, serotype 2 with a long electropherotype; and one strain was of subgroup I, serotype 3. Five group C rotaviruses were detected.

The Relative Frequencies of G Serotypes of Rotaviruses Recovered from Hospitalized Children with Diarrhea: A 10‐Year Survey (1987–1996) in Japan with a Review of Globally Collected Data

“…Eighteen studies reported that none of the rotavirus specimens possessed an unusual combination of serotype and electropherotype. However, several studies reported strains having an unusual combination of serotype and electropherotype (4,6,16,55,57,64,72,74). The frequency of the isolation of these rotaviruses varied from nil (0/605 in New England) (7) to 2.7% (9/335 in Bangladesh) (72).…”

“…1) and G2. Serotype G2 strains possessing long RNA patterns have thus far been reported in six studies (1,6,31,43,65,72), and some were demonstrated by RNA-RNA hybridization to be reassortants between members of the Wa and DS-1 genogroups (35,72).…”

“…In 24 of the 63 studies in which only G1-4 serotypes were examined, the numbers were reported for nontypable specimens that contained rotaviruses whose outer capsid proteins were either retained or whose VP7 genes were amplified by RT-PCR (Table 4). These nontypable specimens corresponded to 8.1% (376) of the total rotavirus specimens that were tested in the 24 studies (6,126). They were most likely to possess serotypes other than G1-4.…”

Epidemiologic features of rotavirus infection in Taiwan: A review

“…Throughout the world, VP7 serotype G1 is detected most often, followed by G2, G3 and G4. 13 Each of the four serotypes has a worldwide distribution, with no single serotype being found exclusively in one location. 6 Serotype G1 is also predominant in Taiwan, as in many reports from all over the world.…”

Identification of a human group C rotavirus in Malaysia

“…Large outbreaks of severe 0 1994 WILEY-LISS, INC. diarrhea in adults have been associated with Group B rotaviruses in several provinces of China [Hung et al, 19841, but not elsewhere. The Group C rotaviruses have been associated with either sporadic diarrheal illness or small outbreaks of diarrhea in infants and children in several different countries throughout the world [Beards et al, 1989;Bonsdorf and Svensson, 1988;Bridger et al, 1986;Brown et al, 1988;Caul et al, 1990;Chen et al, 1988;Dimitrov et al, 1983;Espejo et al, 1984;Matsumota et al, 1989;Nicholas et al, 1983;Penaranda et al, 1989;Rodger et al, 1982;Saif and Theil, 19851. Group C rotaviruses were isolated initially from diarrheic piglets in the United States [Saif et al, 19801, and limited surveys suggest this virus commonly infects pigs in North America, Europe, and Australia [Bohl et al, 1982;Nagesha et al, 1988;Saif, 1990;Saif and Theil, 19851.…”