Temporal and geographical genetic variation in the amphipod Melita plumulosa (Crustacea: Melitidae): Link of a localized change in haplotype frequencies to a chemical spill

pKa’s of Ionizable Groups and Energetics of Protein Conformational Transitions

“…In both cases there is a structural change between two biologically functioning forms of the protein, induced by a shift in pH. Molecular modeling studies of the mechanism of this pH-induced transition for hemagglutinin , as well as for nitrophorins , were already performed, however, using different methods. It is of interest to do similar calculations for these systems using our methodology and to compare the appropriate results.…”

Sharp decrease of genetic variation in two Spanish localities of razor clam Ensis siliqua: natural fluctuation or Prestige oil spill effects?

“…Pollution is known to affect the genetic structure of natural populations (Belfiore and Anderson 2001;Matson et al 2006), either through a direct mutagenic effect of the toxicant or via contaminant-mediated mortality and/or alteration in physiologic or reproductive parameters (e.g., Bickham et al 2000;Theodorakis et al 2001;de Wolf et al 2004a). This is particularly true for species with short generation times and/or with a sessile period of their life including fish, amphibians and many invertebrates (Matson et al 2006;Chung et al 2010). Environmental contaminants can lead to a reduction in genetic diversity resulting from strong selection for chemical tolerance, from an increased mortality, from founder effects resulting from re-establishment of extinct populations or as a result of a reduction in the number of breeding adults (Nadig et al 1998;Matson et al 2006).…”