2024
DOI: 10.1186/s12879-024-09455-1
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Temporal composition of the cervicovaginal microbiome associates with hrHPV infection outcomes in a longitudinal study

Mariano A. Molina,
William P. J. Leenders,
Martijn A. Huynen
et al.

Abstract: Background Persistent infections with high-risk human papillomavirus (hrHPV) can cause cervical squamous intraepithelial lesions (SIL) that may progress to cancer. The cervicovaginal microbiome (CVM) correlates with SIL, but the temporal composition of the CVM after hrHPV infections has not been fully clarified. Methods To determine the association between the CVM composition and infection outcome, we applied high-resolution microbiome profiling us… Show more

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