Temporal course of symptoms and social functioning in relapsing schizophrenics: A 6-year follow-up

Parnas, Josef; Jørgensen, Anne Juul; Teasdale, Thomas W.; Schulsinger, Fini; Mednick, S. A.

doi:10.1016/0010-440x(88)90017-x

Cited by 26 publications

(10 citation statements)

References 35 publications

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“…Finally, the data collection is based on the two chronological nodes — baseline and five‐year reassessment — and is therefore unsuitable to track a more fine‐grained timing of the transitions related to relapse and possible readmission. In this respect, it must be emphasized that, whereas the baseline assessment was related to consecutive referrals and, therefore, coinciding with severe and acute psychopathological states, this was not the case for the reassessment 5 years apart, which is an arbitrary point in the natural history of the illness 37.…”

Section: Discussionmentioning

confidence: 99%

Self‐experience in the early phases of schizophrenia: 5‐year follow‐up of the Copenhagen Prodromal Study

et al. 2011

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Despite the avalanche of empirical data on prodromal/"at risk" conditions, the essential aspects of the vulnerability to the schizophrenia spectrum remain largely unaddressed. We report here the results of the Copenhagen Schizophrenia Prodromal Study, a prospective, observational study of first admission patients in putative state of beginning psychosis (N=151) with a follow-up length of 60 months. At follow-up, the rate of conversion to schizophrenia spectrum diagnosis was 37%, whereas the conversion rate from schizotypal disorder to schizophrenia was 25%. High levels of perplexity and self-disorders baseline scores yielded the best prediction of the subsequent development of schizophrenia spectrum disorders. Escalating transitions within the spectrum (i.e., from schizotypal disorder to schizophrenia) were not associated to any candidate psychopathological predictor.

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Section: Discussionmentioning

confidence: 99%

Self‐experience in the early phases of schizophrenia: 5‐year follow‐up of the Copenhagen Prodromal Study

et al. 2011

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“…The type stability of schizophrenia ranged from 39.3 to 83.3%. This can be compared with other results obtained from hospital records [17], which showed a rate of change of 16% between paranoid and nonparanoid subtypes. In 1985, Kendler et al [18] found a low stability rate among the different subtypes of schizophrenia.…”

Section: Stability Of Diagnosesmentioning

confidence: 95%

Stability of DSM-III-R Diagnoses: Study of a Case Register

Huguelet

Gueddari²,

Glauser³

2001

Psychopathology

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We studied the diagnostic stability and the factors associated with it in 1,443 psychiatric patients with multiple admissions for a period of 45 months. We successively considered the whole population, the psychotic and then the schizophrenic patients. Demographic and DSM-III-R diagnostic information was collected on a computerized database. During the observation period, 1,443 patients were hospitalized twice or more. Diagnostic stability ranged from 34 to 86%. Psychotic disorder was the most stable, whereas adjustment and anxiety disorders were the least stable. Among schizophrenic patients, higher stability appeared for residual and disorganized types (83 and 71%, respectively). Statistical analysis did not show any variable associated with change, apart from the diagnoses themselves. The reasons that could explain changes are discussed, as well as the clinical consequences of these shifts.

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“…(1 7) found divergcnt fcatures for predominantly positive-symptom and predominantly negativesymptom schizophrenia. The subdiagnostic categories of paranoid and non-paranoid schizophrenia show reliably distinct features as well (18). If premorbid signs of these subtypes of schizophrenia are indeed different, then this poses a problem for predictions of the diagnosis of schizophrenia.…”

Section: Introductionmentioning

confidence: 99%

MMPI variables predictive of schizophrenia in the Copenhagen High‐Risk Project: a 25‐year follow‐up

Carter

Parnas²,

Cannon

et al. 1999

Acta Psychiatr Scand

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Moldin et al. (1) have identified a cluster of Minnesota Multiphasic Personality Inventory (MMPI) scales that discriminate adolescents at risk for schizophrenia from those not at risk. The present study examines how well Moldin's scales predict schizophrenic decompensation in a sample of 207 Danish adolescents at high genetic risk for schizophrenia. Subjects were assessed using a modified, 304-item MMPI in 1962 (mean age= 15.1 years) and diagnosed in 10-year and 25-year follow-ups. Premorbidly, schizophrenic subjects (n=31) scored higher than subjects with no mental illness on the frequency (F) and psychoticism (PSY) scales. When paranoid and non-paranoid preschizophrenics were separated, three scales (F, Pz (paranoid schizophrenia) and PSY) significantly discriminated paranoid preschizophrenics. Discriminant function analyses confirmed these results. It is concluded that the MMPI may be useful for identifying schizophrenia premorbidly.

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Temporal course of symptoms and social functioning in relapsing schizophrenics: A 6-year follow-up

Cited by 26 publications

References 35 publications

Self‐experience in the early phases of schizophrenia: 5‐year follow‐up of the Copenhagen Prodromal Study

Self‐experience in the early phases of schizophrenia: 5‐year follow‐up of the Copenhagen Prodromal Study

Stability of DSM-III-R Diagnoses: Study of a Case Register

MMPI variables predictive of schizophrenia in the Copenhagen High‐Risk Project: a 25‐year follow‐up

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